SOCIETY OF TOXICOLOGY, INC.
1972-1973
PRESIDENT:
PRESIDENT-ELECT:
SECRETARY:
TREASURER:
PAST-PRESIDENT:
COUNCIL:

Victor A. Drill
Joseph F. Borzelleca
Robert A. Scala
Donald D. McCollister
Wayland J. Hayes, Jr.
Officers and Councilors, Leon Golberg
(1971-1973), Edward D. Palmes (1971­
1973), Sheldon D. Murphy (1972-1974),

President: Victor A. Drill

John H.Weisburger (1972-1974)

COMMITTEE MEMBERSHIP
Elected Committees
Membership Committee
Educational Committee
Robert L. Dixon (1972-1973)*
George J. Wright (1971-1973)*
Dorothy B. Hood (1971-1974)
Mary O. Amdur (1971-1973)
Frederick Sperling (1972-1975)
Tom S. Miya (1972-1974)
Lauren A. Woods (1972-1974)
Finance Committee
Donald D. McCollister*
Edwin V. Buehler (1971-1973)
Francis N. Marzulli (1971-1973)
Herman F. Kraybill (1972-1974)
Herbert E. Stokinger (1972-1974)

Awards Committee
Wayland J. Hayes, Jr.*
Sheldon D. Murphy
Edward D. Palmes
Board of Publications
Julius M. Coon (1970-1973)*
Gabriel L. Plaa, Managing Editor
Victor A. Drill, President
Ted A. Loomis (1971-1974)
Mary O. Amdur (1972-1975)
Joseph F. Borzelleca, Auditor

Appointed Committees
Program Committee
Joseph F. Borzelleca*
Herman A. Bimbaum
Clifford I. Chappel
Florence K. Kinoshita
Joseph J. McPhillips
Frederick W. Oehme
Orville E. Paynter
Robert A. Scala
Sorell L. Schwartz
Leonard J. Vinson
Anne M. Wolven (Registrar)

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Nominating Committee
Robert L. Roudabush*

Technical Committee
Carrol S. Weil*

David A. Blake

Clifford I. Chappel

Rolf Hartung

Bertram Dinman

Mark Hite

John P. Frawley

Elton R. Homan

Keith H. Jacobson
J.W. Newberne
David P. Rall
Clara H. Williams

Regulatory Affairs
John P. Frawley*
Evelyn G. Burtis
John F. Griffith

Placement Committee

Bernard L. Oser

John E. Keller

Robert L. Roudabush
ad hoc Committees
Committee on Manpower and

Committee to Review

Training in Toxicology

Membership Requirements

Robert Anderson*

Kenneth P. DuBois*

John Autian

John Doull

David W. Fassett

Stephen Krop

Wayland J. Hayes, Jr.

Edward D. Palmes

Harry W. Hays

Ralph C. Wands

Committee on Licensure and Accreditation
Emil Christofano*
Horace W. Gerarde
Herman F. Kraybill
Robert A. Scala
Henry F. Smyth, Jr.
*Chairman

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LIAISON APPOINTMENTS
Representative to Division of

Representative to Science

Chemistry & Chemical

Advisory Committee

Technology National

Registry of Tissue Reactions

Academy of Sciences

to Drugs, National Academy

National Research Council

of Sciences, National
Research Council

V.K. Rowe

Harold M. Peck
Representative to Drug

Liaison Member, Z-37

Research Board, NAS-NRC

Committee

Victor A. Drill

Harold N. MacFarland

Representative to Scientific

Representative to Public

Advisory Board, National
Center for Toxicological

Advisory Committee on the

Research

Drinking Water Standards

Robert A. Scala

Environmental Protection Agency

Revision and Application of

John A. Zapp, Jr.

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TWELFTH YEAR OF THE SOCIETY
1972-1973
The twelfth annual meeting of the Society was held at the Waldorf-Astoria Hotel in New York
City, March 19-22, 1973. Total registration was 769, with 311 members, 415 nonmembers and
43 students.
Dr. Victor A. Drill, President, opened the business meeting by reviewing some of the highlights
of the activities during the year.
(1) A symposium on “Toxicological Problems Affecting the Future of Man” was presented at
the meeting of the International Union of Pharmacology in July 1972 in San Francisco through
the efforts of Dr. Harold C. Hodge, Dr. Ted A. Loomis and Dr. Kenneth P. DuBois. The Society
also sponsored a one day satellite meeting consisting of a symposium on the “Role of Bio­
transformation by Nonhepatic Microsomal Mechanisms in Altering Toxicity,” as well as
individual papers.
(2) At this meeting several members of the Council of SOT held an informal meeting with
toxicologists from abroad, including members of the European Society for the Study of Drug
Toxicity and the Canadian Association for Research in Toxicology. There was considerable
interest in closer cooperation between societies with possible joint symposia, and perhaps in a
few years, an International Union of Toxicology. The European Society agreed to cosponsor a
symposium on “Experimental Model Systems for the Evaluation of Carcinogenic Risks” with
the Society of Toxicology at its meeting in Zurich in June 1973.
(3) A letter was sent to key members of the U.S. Congress offering consultive services of the
Society of Toxicology on legislative matters involving the Society’s capabilities. Several
Senators and Congressmen requested information, which was readily supplied.
(4) A number of members of the Society were asked to review the draft copies of criteria
documents being developed by the National Institute for Occupational Safety and Health. These
covered such topics as cholinesterase inhibitors, mercury and mercury compounds, arsenic and
its compounds.
(5) The Council broadened its liaison representation with other organizations by the
appointment of Dr. Robert Scala as representative to the Scientific Advisory Board, National
Center for Toxicological Research; Dr. John Zapp as representative to Public Advisory
Committee on Revision and Application of Drinking Water Standards, Environmental
Protection Agency.
(6) The Delaney Amendment to the Food, Drug and Cosmetic Act became a controversial issue
and the Council authorized the appointment of an ad hoc committee to review the scientific
issues.
(7) The Council also explored the possibility of a joint meeting with the Canadian Society of
Toxicology when SOT was scheduled to meet in Toronto in 1977.

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(8) Four ad hoc committees were appointed by the Council to consider matters of importance to
the Society: (a) Committee to Review Membership Requirements; (b) Committee on Licensure
and Accreditation; (c) Committee on Regulatory Affairs; and (d) Committee on Manpower and
Training.
The Program Committee accepted 154 titles and abstracts for presentation at the scientific
session.
On Monday afternoon, March 19, 1973, a symposium was held to examine communications
between regulated industry and regulating agencies and to identify those attitudes, practices and
policies that may facilitate or impede this communication. Dr. Harold Hodge was Chairman and
the speakers were:
Dr. Dale Lindsey, Department of the Interior; Dr. Julius Johnson, Dow Chemical Company; Mr.
James H. Marret, Toilet Goods Association; and Dr. Albert Kolbye, Department of Health,
Education and Welfare.
President Drill introduced Mr. William C. Hays, Counsel for the Society, and asked him to
comment on the new Internal Revenue regulations regarding nonprofit organizations. He said
the regulations would have little impact on the Society since its income was primarily from
dues. He also mentioned some of hit activities during the year, such as filing various official
documents, reviewing contracts and getting sales tax exemptions. He thought the growth in
numbers of members and the successful management of the Society’s affairs were indicative of
a healthy organization.
In leaving the office of Treasurer, Dr. McCollister summarized some of the activities that he
and the Finance Committee had dealt with over the past four years:
(1) The total funds on hand in 1969 when the Treasurer took office were $33,455.34. As of
June 1972, the total funds amounted to $40,443.40, yielding a modest average increase of
$1,750 per year. Although the membership dues were increased from $25.00 to $35.00, the
$10.00 increase was taken up by the increased cost of the Journal and paying for an assistant to
the Editor of Toxicology and Applied Pharmacology.
(2) The Treasurer was primarily responsible for instigating action within the Society to change
the fiscal year from July 1 to June 30 to that of a calendar year, January 1 to December 31. This
was approved by the membership at its meeting in Williamsburg in 1972. This was an excellent
move and avoided a lot of difficulties in collecting dues and submitting subscription lists to
Academic Press.
(3) Income from the 11th Annual Meeting in Williamsburg netted the Society about $5,000.
Other income was realized from reprints, advertising, interest and the donation for awards by
the Industrial Biotest Laboratories. Expenses included subscriptions to the journal for the
members, expenses of the Secretary’s office, Merit and Achievement awards and travel
expenses for various members of committees who did not have financial support.
(4) A budget for the calendar year 1973 was submitted to the Council showing a deficit of

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about $5,000, but as in the past, not all of the estimated expenses materialized and thus there
was no deficit.
(5) The Treasurer and the Finance Committee were not pleased with deficit budgeting, but
suggested that the Council wait for several years to evaluate the financial status before taking
action to find additional sources for revenue.
The Membership Committee received 67 applications and recommended 57 to the Council for
approval. The Committee felt that about one-fourth of the applications had borderline
qualifications when evaluated by the criteria set forth in the Constitution and Bylaws of the
Society. They felt that a “continued professional interest” must include the last two years of the
applicant’s scientific endeavors. Toxicology, they said, should be defined broadly and should
include scientists working in related disciplines, such as biochemistry, pharmacology,
pathology, veterinary and clinical medicine. Those “who have conducted and published original
research” should be interpreted to mean that the applicant has been the principal author on at
least two publications in recognized national journals. The Committee thought there was no
need for a Junior or Associate Membership at this time and that a policy be established
regarding “invited” members to avoid any embarrassment should the Committee reject or defer
someone invited to join the Society.
The Education Committee considered two programs. The first involved the compilation of
curricula in toxicology offered in the United States and abroad and urged completion of the task
with updating every five years. The second involved an expression of interest in the review and
evaluation of existing audiovisual materials in toxicology for the National Medical Audiovisual
Center at the National Library of Medicine.
In August 1972, Dr. Gabriel Plaa became Editor of the Journal Toxicology and Applied
Pharmacology. Dr. Ninfa-Indacochea-Redmond served as Editorial Assistant. The Editor and
Associate Editors reviewed 187 manuscripts, accepted 58, rejected 35 and the remainder were
still under review.
The Technical Committee became involved in two very important issues: the first was the
proposed revision by EPA of the test for eye irritants and hazardous substances, which appeared
in the Federal Register April 28, 1972, volume 37, No.83. Carrol Weil prepared his personal
comments and sent them to members of the Technical Committee. Since most of them did not
consider themselves experts in this area, Dr. Drill appointed Mr. Weil to the Technical
Committee to serve as Chairman and to serve as Chairman of an ad hoc Committee to consider
the matter of the proposed revision of the eye irritation test. The ad hoc Committee composed
of Clyde Burnett, Steve Carson, Kenneth Olsen, Robert Scala and Fred Snyder met in
Pittsburgh on September 13, 1972, and prepared a report on the proposed revision and it was
forwarded to the Hearing Clerk by Dr. Drill on September 20,1972.
The second issue involved a notice in the Federal Register, Volume 37, No. 183, September 20,
1972, of EPA’s Proposed Toxicology Guideline. This was brought to Mr. Weil’s attention by the
Chairman of the Regulatory Affairs Committee, Dr. John Frawley, who thought the Society
should take a strong position since it would standardize protocols and require strict adherence

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to rigid government specification and be devoid of professional judgment. Dr. Drill requested
the Technical Committee to prepare a response, stating the Council’s concern. Mr. Weil again
met in Pittsburgh with several members of the Committee and drafted a report which was sent
to the Hearing Clerk on December 6, 1972. The report offered a series of guidelines as a
substitute for the proposed rule.
The first committee to consider the matter of Licensure and Accreditation, chaired by Dr. Emil
Christofano, suggested that the Society establish a financially self-supporting program for
certification of persons evaluating safety of chemicals. By a combination of training and
experience some members, they said, are generally recognized as experts and should be
certified without examination, while others who have not achieved general recognition as
expert, an examination may be necessary. The Committee urged the Society to implement a
certification program.
At the meeting of the Society in 1972 a group met informally to discuss a proposed conference
on education in toxicology. The discussion quickly turned, however, to the need for more
information about training in its broadest sense and the manpower needs to which training
should be geared. This subject was the main topic for discussion at the Past Presidents’
breakfast and all agreed that a study on manpower and training was highly desirable, and by
June, an ad hoc committee was appointed by the Council. On February 1, 1973, 61
questionnaires on Training and Employment were sent to universities and 79 to industrial and
commercial laboratories. As of March 6, 16 universities and 19 industrial laboratories had
responded. Although it was too early to draw any meaningful conclusions, it appeared that not
only was there a need for more toxicologists but a vastly improved teaching program. The final
report was planned for 1974.
The liaison members representing the Society in various activities, as shown in the
organizational format, continued aggressively to participate in the discussion, and urged the
Council to continue the Society’s representation.
The Director of the Placement Service, Dr. John Keller, reviewed 121 resumes of candidates
seeking employment and processed 31 available employment positions. It was believed that 12
candidates were known to have found employment.
At the banquet on Tuesday evening, March 20, Dr. Victor A. Drill presented the Merit Award to
Dr. Herbert E. Stokinger for his outstanding contributions to toxicology and related disciplines
and his never-ending efforts to stimulate young scientists to work in toxicology. The guest
speaker was Professor Seymour Lewin, Department of Chemistry, New York University, who
spoke on “Toxicology of Monuments,” a discussion of environmental pollution on monuments
and public buildings.

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