FILE NAME: Texaco (TEX)

DATE: 2003

DOC#: TEX027

DOCUMENT DESCRIPTION: Tables of Contents & 1 Article by Heuper
found in Texaco Library

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OCT 17 2003

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SUPERIOR COURT OF WASHINGTON FOR SKAGIT COUNTY

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VIRGINIA JAMESON, Individually and as
Personal Representative o f the Estate o f
RAY JAMESON
Plaintiffs,

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V.

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TEXACO, INC. e t al.

No. 02-2-01069-8

DECLARATION OF
MIKE CHASE

Defendants.

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I, MIKE CHASE, declare and state as follows:

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1.

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I am over the age o f eighteen and make this statement based upon peisonal

knowledge.

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2.

I am an investigator in Beaumont, Texas.

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3.

Recently, I w ent to the library o f the Lamar University in Beaumont, Texas to

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look for volumes from industrial hygiene journals purported to have been donated by the Texas

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Company to Lamar University.

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4.

In the course o f m y research I was able to locate several volumes dating from the

early 1950s o f the journal called Archives ofIndustrial Hygiene and Occupational Medicine.

Bergman S enn P ageler s F kockt

DECLARATION OF MIKE CHASE. -1
caowmmmwa t

utrci KidomiPmD-PB: op HucflCrtNSB.*«

Í .O . BOX 2010, 11530 Vittimi Hjranu« 6H
vmnoh, WA 96070
TKtiEMW«*« 206.463.440B
FaCbJkZLS: 2 0 6 .4 6 3 .4 4 7 0

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According to the title page o f each volume, this particular journal was published by the

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American M edical Association.

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In the volumes, the title pages and, in some instances, the table o f content pages,

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contained the following information appearing to be in the form o f an ink stamp: “THE TEXAS

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COMPANY LIBRARY RESEARCH LABORATORY PORT ARTHUR TEXAS.”

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Attached to this declaration are true and correct copies o f title pages and table o f

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contents pages o f five volumes o f die Archives O fIndustrial Hygiene and Occupational

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Medicine spanning the years 1951 to 1955. I personally located and had copied these pages

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directly from volumes that were on the shelves in the Lamar University library, a public

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institution in Beaumont, Texas.

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I declare that the foregoing is true and correct under penalty o f perjury.
DATED this 17th day o f October, 2003 at Beaumont, Texas.

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fl/ljJ

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___________________

MIKE CHASE
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Bergman Sen» Pageusr t Frock?

DECLARATION OF MIKE CHASE. - 2

P.O. BOX 2010, 17530 VXsHoh
VXflBOM, HA 90070
TsumONEt 200.(03.4408
E M n m st 200.403.4(70

SW

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Industrial Hygiene
and

Occupational Medicine

e d it o r ia l

board

PHUTI* MUNHEH, CHW ¿011«
Sí S U tt» * .Street. PorHo I t

TUBO)IIIHG r . BATCH, lAilsibuiAh.

IBUf » PUOI JR. Oleato)», C»IH.

MMKitT a. aojos, cinerontai

ruAHK t w u i vautt

SHILNK A, fA ITTi U*W#i

WILLIAM A. \»WTBH, »*AcO*r. N, T,

JAME) It. BTBSWJfH. Tludiokr, » . Y.

'

MCHATID I. PLUNKCTI, M.D., CblMSA Muiutág lUü«r

Volume 3
1951

FUBUSnEBB
AHE&IGOI MKUICAL ASSOCIATION
CHICAGO ID, ILL.

CONTENTS OF VOLUME 3
JA N U A R Y

1951. N U M B E R

1
PACE

ttioerim ental Studies of Asbestosis. A rth u r J. Vorwald, Ph.D .(J
^ 5 D urkan and Philip C. P ra tt, M .D , Saranac Lake, N . Y>.
A ir Pollution in Pittsburgh, Sumner B. B y , S.B„ P ittsburgh................................................

44

Toxicologic Studios of Compounds Investigated for Use as Inhibitors of Biologic Processes.
Anthony M. Ambrose, F b -D , Albany. C alif.:
I I I . Toxicity of Propylene Glycol Dipropionate........ ..................... .......... ................. 48
IV , Toxicity of l^-Dim «thyl4,6-Bxs(Chlorom ethyl) Benzene............... ................. 52
investigation of Occupational Dermatoses in tf«s Citrus F ru it Canning Industry. Donald J.
lnV p tS J w rh**», l ü T j P au l C. Campbell J r , H D .} H a iry N . Doyle, B .S , Washington,
D . C , and J . M. hfeDonuld, M .D , Jacksonville, F la...................... . . . . . . . . . . . . . . . . . . S7
A' Study of W orkers Exposed to the Insecticides Chlordan, A idrin, Dieldrin. F ran k Princi,
M JD, Cincinnati, and George H . Spurbcek, M J 5 , Pierre, S. D.................................. .
64
An Analysis of E xisting Types of Small-PJant H ealth Services in Northeastern United .
States. R. B, O'Connor, M .D , B o s to n ..........................................................- ..................... 73
Experimental Beryllium Granulomas of the Skin. F ran k R. D utra, M .D , Cinckmati..........

81

Meteorological Technics in A ir Pollution Surveys. M erril Eisenbud and W . B. H arris,
New Y ork................................................................................. ♦................................................... #>
New Instruments and T echnics:
A Modified A ir Sam pler Employing Fiberglas-* F . W . Schl and B. J . Havens J r , .
Hartford, Conn..........................
98
Abstracts from C urrent L iterature.........................................................................

101

News and Comment.......... ............................ ..................................................................................... 115
Book Reviews................................................................................................................................
FEBRU ARY

1951. N U M B E R

2

A Rapid X -R ay Diffraction M ethod for the Determination o f Q uartz in Industrial Dusts.
Lawrence L. Sehmelzcr, B .S , Berkeley, C a lif............................................ .............
121
Significance o f the Exercise Tolerance T est. W illiam F . R outer, M .D , Baltimore................ 129
A Study of Nitrogen O xide Concentrations D uring A rc W elding. Leslie Silverman, Sc,D.
(Indust. H yg.) and S. 1. H usain, S .M , Boston.............................................................. .
155
Symposium on the Dynamics o f Industrial H ygiene;
Presentation of an Unidentified Occupational Case H istory. Robert J . Hasterlik,
M iD , Chicago..........................; ................... ....................................................................... 147
Surveying the P lant, D . J . Lauer, M .D , Cincinnati............................................................. 150
Studying the Environment. F . E . Adley, Richland. W a s h . . . . . . ..................................
153
Chemical Analysis. Francis R . Holden, Ph,D.(Chem.), San Francisco........................... 159
Maximum Allowable Concentrations. H . H . Hudson, M JD , Nashville, T a m ................... lfii
Medical Control. Robert A . Kehoe. M D , O o c m n a ti.,.............. .................... ............... ifi$.
The Engineering Control of an Occupational H ealth H azard, B. F , Postman, M ,E ,
New Y ork......................................... ............................... ......................................... . ..7 7 . 159
Hi

120

CONTENTS OF VOLUME 3
FE B R U A R Y —Continued

PACE

On the R
Traci

Symposium on H ow Industrial Medicine Can Meet the Needs of th e American W orker:
T h e Viewpoint of the Personnel Administrator. H iram S. H all, A .B , LL.B „ New Y ork 173
T he Viewpoint of the Sociologist Relnhard Bendix, Ph.D ., Berkeley, Calif................... 177
T he Viewpoint of the Psychiatrist. K arl M. Bowman, M -D , S an Francisco............... . 181
T h e Viewpoint o f the Physician in Industry. H enry H . Kessler, M.D-, Newark, N . J L . 185
The Viewpoint of die Union. H a rry Read, W ashington, D. C ................... ................. • • • 188
T he Viewpoint of Religion. Richard Henry, B.D., Knoxville, T enn............... ................192

Effects O
eatioi
Belle

Value an
Arth'
Evalua tin
Ah In

New Instruments and Technics :
A Lightweight Pow er Supply for an Electrostatic Precipitator. John K . Brown, B.S.
(Chem. E n g r.) ; Andrew D . Hosey, B.S.(Cftcro, E n g r,), and H erbert H . Jones,
'
B ,S ,(C E .), O n clm u ti.............. ......................................... -,...............■ ......... - .............. 198
Abstracts from C urrent L iterature.......... ...................... ...........................................................

204

News and Comment........ , .................................. 1 . . . . ............. ......................................................... 224
Book R e v ie w s ....,,........................................................ «.................................... ............................. 226
M A RCH

»51.

N U M B ER

Health ai
ingto
Rose
Abstract!

1

News a r
Book R e

3

Effects of Noise on Human Behavior and Communication. H allawell Davis, M .D„ St. Louis 227
Noise In Industry: Report of a Conference H eld D uring the T enth Annual Congress on
Industrial Health, of die American Medical Association, in N ew York, Feb. 20„t 1950.
' James H . Sterner, hf-D., Rochester, N . Y , and Stacey R . Guild, P h .D , Baltimore,
Co-Chairmen ..................................................................................................
232
Physical Medical and Rehabilitation Therapy of H and Injuries. H erm an J . Flax, M .D ,
San Juan, Puerto Rico........................................................................ *.............................
236
Occurrence of D D T In Human F a t and Milk. Edwin P . Laug, P h J> .; Frieda M. Kunze,
B .S , and C, S. Priekett, M .S., W ashington, D. C................. *............... .............................. 245

Fatalità.
Jack
A Toxi
Sha
C rit
Aiding i
Air Fio
Ser
P io

Hydrogen Sulfide Poisoning m Shale O il Industry. Gunnar Ahlborg, M -D , Stockholm,
Sweden ...............
24?

Chroqic
Ph.
A lt

Treatm ent of Lead Poisoning with Sodium C itrate: Report of F o u r Cases. H arriet L.
Hardy, M .D , Boston; Ronald C. Bishop, M .D , Roxbury, M ass, and Clarence C
Mai oof, M .D , Boston............................................................................................................
267

Activlti

A Pilot Program for Cancer Detection in Industry. Benjamin N . Berg, M .D , New Y o rk .. 279
Toxic Effects of Exposure to Vapors of Aliphatic Amines. H einrich Bricgcr, M .D , and
W illiam A_ Hodes, A .B , Philadelphia....................... ......... ....... . . . . . . . . . . . . . . . . . . . . . . . . 287
Compensation Aspects of Myocardial Infarction in Industrial Medicine. James H .
Thompson, M .D , San F ra n c is c o -............... ..................................................................
292
Report on Industrial Hygiene in the W estern Zone of Germany.
M .D , New Y ork......................

Wa
Cadmiti
Investii
Da
Abstrai
News :

Irving R. Tabershaw,
298

New Instruments and Technics:
A Smalt Self-Contained Laboratory for Radioisotope Studies hi Experimental Animals.
Reidar F . Sognnacs, D.M JO, F b .D , and James H . Shaw, P h .D , Boston................. 316
Abstracts from Current L iterature.............................................................................. ...................323

Chroni
T»
Case «

News and Comment................................................................................................

338

Book R e v ie w s...........................

338

Five C
im
W

Report on a Country-Wide Study of Silicosis in the Metal M inci of Japan, Mikio Yama­
moto, M T ), Tokyo, J a p a n ,...................................................................................................... 339

Chron-

A P R IL

1951. N U M B E R

4

Present Condition of W orkmen’s Compensation Laws, and Possible Changes. Marshall
Dawson. Washington, D . C . ....................................................................................................350

H;

Spenti
tu

CONTENTS OP VOLUME 3

J

APRIL—-Continued

TAGS

n « the Retention of A ir-B orne Particulate* in the Human L ong: II . H . D, Landahl, T . N .
Tracewell and W . H . Lassen, Chicago.................................................................................« 9

irk 173

effect* of Employment on th e Course of H eart Disease. T h e Steff o f % W o rk Clmssifi* cation Unit, A dult Cardiac Clinic, T hird (N ew Y ork U niversity) Medical Division,
Bellevue Hospital, New Y o jk ...................................................... .......................... • • .............. 36’

... m
. . . 181

... IBS

. . . 188
. . . 192
B.S.

PACE

Value and Operation of an Industrial Medical Program . M ax N . Howard, M.D., and
A rthur E . H oag, M.D* New Y o rk .......................................................................................... 375
Evaluating Trichloroethylene Exposures by Urinalyses for Trichloroacetic A dd. A xel
. Ahlmark, MX».. Stockholm, Sweden, and Sven F orem an. M.D„ Tomteboda, S w eden.. 385

198

Health and A ir P ollution: A Study on a Limited Budget, H arry Hermann, M.D„ W a sh '
ington, D . C .; W . F . Reindollar. ScX>, Baltimore; H ugh P . Brinton, Ph.D., and
Rosedith Sitgreaves, M.A., W ashington, D. C -.................................................................... 399

*♦ fte 204

Abstracts from C urrent L iterature.................................................................................................... 408

224

New* and Comment............................... - .......................*......................................*...........................44Z

22$

Book Reviews................................................. • ••» .................................................................................442
MAY

Louis 227
** on
1950.
¡more,
........ .2 3 2
M.D.,
...........236
Kimze,
. , ... . 245

f

v

,i

247

rriet L.

1951, N U M B ER

S

Fatalities from Hydrogen Sulfide In W ells. John M. McDonald, M .D , and A . P . McIntosh,
. Jacksonville, F la..................... .................................................. *.............................................
445
A Toxicological Study of Some Polypropylene (Polyoxpropylcne) Glycols. C. Boyd
Shaffer, Ph.D . (P hysiol.); Charles P , Carpenter, Ph.D.(M ed. S c .); Frances H .
Critchfidd, M .S .; John H . N a lr III, M.S., ana Frederick R . Franks, M .D„ Pittsburgh 448
Aiding the Cardiac P atient In Industry. Edw ard M. Kline, M.D., Nela Park, O ev elan d .. . 454
Air Flow Measurements on Human Subject* W ith and W ithout Respiratory Resistance at
Several W ork R ates, Leslie Silverman. S c X .(In d u st H yg.) j George L e e 'T h e o d o re
PlotWn, A .B .; Leonore Amory Sawyers, A.B., and Anne R . Yancey, A.B., B o sto n ...- 461
Chronic Toxicity of the Mcthylpolysiloxane “D C Antlioam* A " in Dogs. George P . Child,
Ph.D., M X .; H enry Osmond Paquin Jr., M.D„ and W illiam B. Deichmann, Ph.D..
Albany, N . Y .......................................... ...................................................................................... 479
Activities of State and Local Agencies in Industrial H ealth. Victoria M, Trasko,
Washington, D. C ...................................................................................................................... 483

Y o rk .. 279

Cadmium Poisoning. Lawrence H . Cotter, M.D., and B. H . Cotter, MX)., New Y ork.......... 495

X ), and

Investigation o f Small, A irborne Charged Particles by an Electrical Method. J. H .
Darnel, Sc.D.(Physfcs), and F . S. Brackett, P b X .(P bysics), Bethesda, Md...........
505

287

Abstracts from C urrent L iterature..................... ......................................................... .................... 520

sues H.

News and C o m m e n t........................................................................... ............................................ 541
fbenhaw,
298

316
323
338
338

lo o Yama-

1951. N U M B ER

6

STMPOSKIM ON THE TREATMENT or CHRONIC »BBYlinW fOISOMING
WITH ACTS ANS CORTISONE
.
♦
.
Chronic Pulmonary Interstitial Granulomatosis: Prelim inary Report on Tw o Patients
Treated w ith A C T H . Joseph M. De Nardi, M X ., Lorain, O hio......................... ........... 543
Case of Chronic Beryllium Poisoning from Atomic Energy Development,
Hasterlik; M.D., Chicago........... .............................................................. 547

Robert J .

Five Cases from th e Fluorescent Lamp Industry; Treatment of Chronic Beryllium Poison­
ing with A C T H and Cortisone. Edward M. Kline, M .P .; Scott R. JnWey, M .D , and
W hiter H . Pritchard, M X * Cleveland.................................................................................... 549
Chronic Berylliosis in the Neon Sign Industry. 0 . A . Sander, M .D , M ilw aukee,............

339

k 'M arshall

JU N E

350

565

Spontaneous Remission of Chronic Beryllium Poisoning from Fluorescent Lamp Manufac­
turing; R eport of a Case. John W . Cass Jr-, M X ,, Brookline, Mass........................... 569

'

JU N E —Continued
PAGE

Chronic Beryllium Poisoning, of Long D uration from Fluorescent Lamp M anufacturing;
R ep o rt of a Case. George K . Fenn, MJD, Beverly. M ass..............................................
571
Beryllium Disease "from th e Ceramic Industry: R eport of a Case. Preston W . Reynolds.
M .D , Schenectady, N - Y . . . . ................... ...................................................................................575

Volvmb 3

Metabolic Study of a O w e of Chronic Beryllium Poisoning T reated with A C T H . H arrie t
L- H ardy, M .D .; Frederic C. Bartter, M B , Boston, and A braham B . Jaffln, M.D.,
Jersey City, N . J . .......................................................................................................................... 579
Choice of Drugs and Dosage. Howard S. V an Ordstrand, Cleveland.......... ................. .

583

Recognition and P reten tio n of the Complications of A C T H and Cortisone Therapy. Thomas
F . Frawley, M D ., Boston ...................................................... .................................................. 587
Information Gained in P retherapy'and Post-Therapy Pulmonary Function Studies. John
M cdem ent, M D , N ew Y ork........ ............................................................................................5 »
Pulm onary Function in Patients w ith Pulmonary Disease T reated w ith A C T H - , B< G.
F e rris J r , M JD.; J . & A ffddt, M .D .; H . A . K riete, A JB , and J . L . WWttcnberger,
M J > , B o sh * . . . . ............................................... ....................................................................... » 603
Interpretation of Résulté o f A C T H and Cortisone Therapy In Chronic Beryllium Poisoninert D ata Obtained b y Pretherapy and Post-Therapy Studies of Pulm onary Function.
G eorge W . W right, M ,D , Trudeau, N . Y ................................................................... .......... 617
Minimum Observations Necessary to Advance Knowledge of th e Action o f A C T H and
Cortisone. Anne Forties, M J ) , Boston....................................... .............. .......... ..
622
C urrent Research Problems Concerning Pulm onary Granulomatosis in Beryllium W orkera. Friedrich Klemperer, M .D , Trudeau, N . Y ......... ............................... .........................625
General Discussion on the Treatment of Chronic Beryllium Poisoning w ith A C T H and
Cortisone ......................................................................................................................................... 629

A

H ealth H azards in the Production and Handling of Vanadium Pentoxide. Sven-G5sta
SjSbcrg, M .D , Eskilstuna, Sweden............................................ ........... ...................................631
N ews and C o m p i e u t - ........................... .............. .........................- .......................... ..

647

Book Reviews ................ ..................................................................................................... *............... 646

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Industrial Hygiene
and

Occnpational Medicine
E D IT O R IA L

BOARD

PHILIP DMNHER, Chief Editor
55 S&attücS Street) Boston J5
THEODORE F , BATCH, PttU bnrgh

FENN E, POOLS, Glendflle, C«Uf.

ROBERT A. KEHOB, C incinnati

FRANK FRlNCI, Denker

FRANK A . PATTY, B e tr itt

WILLIAM A. SÄWYER. RocResUr, N. Y.
JAMES H. STERNER, Rochetrttr. N, Y.

RICHARD 3. PLHNKEJT, HA»., ChlOfigo, Monatftng E ditor

Volvub 4
1951

PUBLISHERS
AMERICA« MEDICAL ASSOCIATION
CHICAGO 10, tVL.

CONTENTS OF VOtUME 4
JU L Y

1951. N U M B E R

1

PAGE

A Method of Obtaining Reproducible Breath Radon Samples. John H . H arley, M .S .;
Evelyn Jetter, and M crril Elsenbud, New Y ork........ .......................................................

I

Industrial and Forensic Applications of Electroencephalography. Joseph L. Fetter man,
M JX , and V ictor M , Victoroff, M.D., Cleveland................................................................

10

Control of D usts by W ater Mists. Kenneth W , Nelson, B ^ d , S alt Lake Q ty ..................

25

Symptomatic Treatment of the'C om m on Cold. Ronald Forbes Buchan, M .D , C M .;
Alfred E . Gras, M.D., and F ran k H . David. A .B , A J3 A , Newark, N . J ...................

32

Arsine*. Electrocardiographic Changes Produced in Acute H um an Poisoning. C arl J.
Joscphson, M .D .; Sherman S. Pinto, M.D., Denver, and Samuel J. Petrondla, M.D.,
E ast Chicago, I n d ......................................................................................................................... 43
Toxicity of Carbon Monoxide and Hydrogen Cyanide Gas Mixtures *. A Prelim inary Report.
R. H . Moss, C, F . Jackson, and J. Seiberlich, Durham, N . H .......................... ............ .

53

Persistence of Beryllium Oxide in Lungs A fter Inhalation of Dust- F ran k R . Dutra, M i l . ;
Edward J. Largent, A .B .; Jacob Cholak, C h £ ,; Donald M. Hubbard, Ch-E., and
James L, Roth, Cincinnati................................................................ ....................................... 65
Study of Eye Irritation Caused by Los Angeles Smog. Richard D . Cadle, Fb.D . (C hcm .),
and Paul L . Magill, B .S , Stanford, CalK .........................................; . . . • ............................ 24
New Instruments and Technics:
Determination of Naphthalene in A ir. M . Cllain Robbins, B.S., Los Alamos, N . M ....

85

Abstracts from C urrent Literature....................................................................... .........................

88

News and C o m m e n t.............................................................. .............................. ........................ 100
Book Reviews.....................................................
A U G U ST

102

1951. N U M B E R 2

Size of Cuttings Produced by Pneumatic D rilling w ith Different K inds of Detachable
Bits. Carlton e . Brown, C h E , Sc,D. (In d u st Hygiene), Frederick, M d ......................103
Range-Finding Toxicity D ata; L ist IV . H enry F . Smyth J rH F E D .; Charles F . Carpenter,
P h D , and Carrol S. Weil, M A , Pittsburgh........................................................................ 119
Epidemiology of Beryllium Intoxication. James H . Sterner, MJX, and M crril Eiseftbud,
New Y a r ik .,.................................................................................................................................. 123
Organic Pesticides—New H ealth Hazards. Justus C. W ard, M .S , Washington, D . C . . . . . . 152
Generation of Phosgene During Operation of Trichloroethylene Dcgreaser- Louis W .
Spolyar, M .P .; R . N. H arger, P h .D .; J . F . Keppler, Ch.E., and H . E . Bums ted,
C h X , Indianapolis...................................
.1 5 6
Special R ep o rt;
■

•

Research on H ealth Education in Industry.............................................................................. 161
Hi

>v

CONTENTS OF VOLUME 4
A U G U ST —Continued

A bstráete from Curren» Literalure.
New» and C o m m en t..................... <.
Book Reviews.....................................
SE P T E M B E R

19S1, N U M B E R

3

Methyl Bromide Fumigation and Control In the Date-Packing Industry. Fred R. Ingram,
M .S., Berkeley, C alif................................................................................................. .............. ly j"
Arsenic and Cancer: O bsem tions in the Metallurgical Industry. Leonid S, Snegireff,
M JD , and Olive M . Lombard, S.M., Boston...................................................... ................... 199;
Effect o f Bituminous Coal Dust and Smoke on the Lungs—Animal Experim ents; 1. Effects
on Susceptibility to Pneumonia. Frederick J . Vintinner, Sc.D , Concord, N . H-, and
A nna M . Baetjer, Sc.D , Baltimore..................... ................................ .................................. j
Effect of Aluminum D ust on Susceptibility to Lobar Pneumonia—Animal Experiments.
i
Frederick J, Vintinner, Sc.D , Concord, N . H ....................... ................. ............
Etiologlc Factors in BroncMogenic Carcinoma, with Spedal Reference to Industrial
E xposures: Report of Eight Hundred Fifty-Seven Proved Cases. E rnest L. Wynder,
M.D., New York, and Evarts A. Graham, M JD , S t L o n i s . . . . . . ........................... .
221/
Evaluation and Significance of Physical Fitness fo r Moderate W o rk : A Study of Patients
w ith Cardiovascular or Pulmonary Diseases. Robert A . Bruce, M.D„ Seattle; Frank
W . Lovejoy J r , M .D .; Paul N. G. Yu, MJD., and Marion E. McDowell, M.D,
Rochester, N . Y ..................................................... ..............................................................
i
Beryllium Excretion in Humans. F. W , Klemperer. M .D.; A. P . Martin, and J. Van
i
Riper, Saranac Lake, N . Y . . . . . . . ............................. .......................................................
Clinical Observations on the Toxicology of Boron Hydrides. H . M. Roaendnat, M-D,
Schenectady, N . Y .................. ................................................................................. ............. - .5
Toxicology of Two Butoxypolypropylene Glycol Fly Repellents. Charles P . Carpenter,
P h ,D .; Frances H . Critchfield, M .S.; John H . N air I I I , M .S , and C. Boyd Shaffer,
1
P h JD , Pittsburgh............... ........................................................................................ .
Coal W orkers’ Pneumoconiosis: Pathological and Etiological Considerations. A. G,
Heppleston, M i . , M .R.C.P, Cardiff, W ales................... ................................................. *
A bstracts from Current Literature.............. .................................................................................. ^
N ews and C om m ent......................................................................................................................... 20$;
O CTO BER

1951. N U M B E R

4

SYMPOSIUM OH A CANCER CONTROL PROGRAM FOR HIGH-BOILING
CATALYTICAUY CRACKED OILS
Teamwork in Control of Occupational Diseases: A n Introductory Statem ent Robert
• Collier Page, M -D , New Y ork....................................................................... ......................... 3
Experimental Analysis of the Carcinogenic Activity of Certain Petroleum Products. William
B. Smith, MJD.', Douglas A. Sunderland, M .D , and Kanematsu Sugiura, Sc.D,
..
New Y o rk......................... .............................................. ............. ............................................... 299 Properties of High-Boiling Petroleum P roducts: Physical and Chemical Properties os
Related to Carcinogenic Activity. H . G. M. Fischer, E E . ; W illiam Priestley J r , M.S.;
L. T . Eby, P h .D .; G. G. Wanless, B .S c, and John Rehner J r , PhJD , Linden, N- J -

v

CONTENTS OF VOLUME 4
)

OCTOBER—Comtimti

_.J

PAOB

C anttr-C bntrol P rogram fo rH Ig h -B o iik g Catalytically Cracked Oils. J . P . H olt, M.D.,
p |iJ ), j N , V . Hendricks, B.E., C h.E .; R . E, Eckardt, M D , P h .D .; C L, Stanton,
JJ.S., and R . C. Page, M .D„ N ew Y o r k . . . ........................................................................ . 325
opertiei of H igh-Boiling Petroleum Products ^Q uantitative Analysis of Tumor-Response
B ata Obtained from the Application of Refinery Products to the Skin of Mice. F . H .
Blending, M .S .; W . H . K ing Jr., B.S.; W illiam Priestley Jr., M .S , and John Rehncr
Jr., P h D.. Linden, N . J .................................................................................................................. 335

f o r Deposition and Retention of Inhaled Insoluble Particulates. H . E. Stoldnger, Ph.D.,
Cincinnati; L. T . Steadman, P h .D .; H . B. W ilson: G. £ , Sylvester; S. Dziuba, B.S.,
and C W . LaBelIeAM A , Rochester, N . Y ... . . — ........................................................... 346
gdngement o f D ust from A ir Jets. C N . Davies, D .S c, F .In st.P .; M ary Aylward, and
Dorothy Lcaccy, London. E ngland............................................................................................ 354
*rtii Reports:
Threshold Lim it Values for 1951 Adopted a t the Meeting of the American Conference
of Governmental Industrial H ygienists in Atlantic City, N . J , in A pril, 1951.......... 398
»tracts from C urrent L i t e r a t u r e . . . . . . . . ..................................................................................401
sws and C o m m e n t................................................................................ ........................................ 414
Mk Reviews........................................................................ ................................................................ 415
N O V E M B E R 1951. N U M B E R 5
•eatment of Cyanide Poisoning in Industry. J . H . Wolfsic. M .D- Linden, N . J . , ................417
to f" nd Labor-Saving Devices in the Industrial Dispensary. Jean Spencer Felton, M.D,,
f' JRidga, T ens.
•
•
•
IV , Clinical-Record Distribution Box for Physician's O f f ic e ....,..............................426
V. Optical Dispensing U n it................. ....................................................................................................................................................................................432
V L M ultipurpose Central Clerical Desk for Treatment Room............................... ..
437
-Ray Diffraction Study of Sputum in Silicosis. F ran k Meyer, M .S c, and Saul Solomon,
' M .D , New Y o rk ............................................. ......................... •.............................. ................... 443
w n cteristk s of the Suction Soap Film M eter: The Suctionometer—a N ew Low-Velocity­
Measuring Device. B ernard D. Bloomfield, S.M., and Leslie Silverman, ScJD, B o sto n ., 446
.•ellndnary Observations on Toxicity of. Elemental Selenium. Robert H . H all. P h J ) .;
Sidney L askin, A .B .; Paul F rank, A R .; Elliott A. Maynard, Ph.D., and H arold C
Hodge, P h.D ., Rochester, N-Y............................................................................................. . 458
■ W ttx of Rodents to Repeated Inhalation of Vapors o f Tetraethyl OrthoeiKcate. U . C
Poizanl, M .S , and C. P . Carpenter, P h D ., Pittsburgh........................................................ 455
*Por Toxicity o f Trichloroethylene Determined by Experiments on Laboratory Animats.
E . M. Adams, P h D .: H . C Spencer, PhJD,; V . K . Rowe, M .S.; D. D. McColHster.
B R , and D . D . Irish, P h .D , Midland, Mich.......................................................................... 459
•por T oxkity of Ethylene Dichloride Determined by Experiments on Laboratory Animals.
H . C Spencer, Ph.D.S V . K . Rowe, M S .: E . M. Adams, F h.D .j D . D. McColileter,
B R , and D . D . Irish , P h .D , Midland, Mich,........................................................................482

1* Toxicity o f an Imidaaolin« (or Glyoxalidinej. Fungicide, Charles F . Carpenter, PhJD .;
Carrol S. W ell. U A , and H enry F - Smyth J r , P h .D , Pittsburgh......................... .

494

CONTENTS OF VOLUME 4

vi

K O V R m W -C m tim td
FACE
A bstracts from C urrent lite r a tu re , r .......................................................................................... 504
N ews and Comment.................................................. .........................................................................
.

D EC E M B ER

518

VoHJMS 4

1951. N U M B E R 6

Benzidine (4,4'-Diaminobiphcnyl) and Substituted Benzidines: A Microchemical Screening
Technic for Estim ating Level* of Industrial Exposure from U rine and A ir Samples.
J. M , Glassman, Fh.D ., Philadelphia, and J. W ister Meigs, M.D., N ew H aven, Conn..-. 519

A i

A Study of Exposure to Benzidine and Substituted Benzidines in a Chemical P la n t; A P re ­
lim inary R e p o rt J . W ister Meigs, M .D .; Robert M . Brown, M .P 3L , and Lonis J .
S d a iia i, PhJD., New Haven, C o n n . . . . , . . , ............................................................................ 533
Rehabilitation of Persons w ith Pulmonary D ust Disease. 0 . A . Sander, M J X M ilw aukee.. 541
Flatinosis'- A Five-Y ear Study of the Effects of Soluble Platinum Salts on Employees in a
P latinum Laboratory and Refinery. A , Eaton Roberts, M .D , Malvern, P a ........... ........... S49
A ldrin Poisoning in M a n t R eport of a Case, Lieutenant Eugene J . Spiotta, Medical Corps,
U nited States A rm y........................................... - ......................... .........................*.................560

I

T IS WIDE
individuals

T h e Chylomicron Count as an Indicator of Phosphorus Poisoning t A Study Utilizing
Experim ental Animals. R . B. L, Fleming, B.S., M.S,, and 6 . H . Collings Jr., M ,D ,
M .P 4 L , W ilson Dam (Sheffield P.O .) A l a . . . . . . . . . . ........................................................ 567

accumulates ir
based on data
occurring amo
bone as distitu
most of which
The radio
mate the radi
A direct c
of gamnu ra
RaC). The
of tolerance
following thi
Radium «
to interpret
with conditi
The am
exhaled bre
radium con
to indicate

Toxicity of D i-(Acetyl Cyanide). Joseph F . Treon, P h ,D .; Frank R . Dutra, M J ) , and
John Cappel, B.S., Cincinnati.............. ........................................................... ....................... 573
Absorption and Excretion of Inhaled Fluorides. Gilbcart H . Collings J r„ M.D., M .P .H .;
Richard B. L. Fleming, M .S , and Roy May, M .S , W ilson Dam (Sheffield P . 0 . ) , Ala. 585
Occupational Diseases of Dentist*. F ran k J. Orland, D.D.S., Ph.D, (B a c t), Chicago.......... 591
T he Instituto of Occupational H ealth in Helsinki. Leo N oro, M J)., Helsinki, F in lan d ......... 597
Abstract* from C urrent L iterature.................................................................................................602
News and Comment......................... ...................................................................................

618

Book Review*.

621

4

From t l
Y o rk Opera'
Present«
Atiantic CSr
1. Hand
19«,
Z E ra r
Radium, J .
3. M ar
and Hahdli
4, He*
the Hmnar
of Radium
102.1947.

A. M . A.
A B C H I V E S

OF

Industrial Hygiene
and

Occupational Medicine
E D IT O R IA L

BOARD

PHILIP DRINKER, C hief E ditor
SS S hatfoek Street, Boston IS
THEODORB F . HATCH, Pittsburgh

OSCAR A . SANDER, M ilw aukee

PENN B , POOLE, G lendale, C alif.

WILLIAM A . SAWYER, R ochester, N . Y .

FRANK PR1NCI, C incinnati

HERBERT E. STOKINGER, C incinnati

JAMES »1, STERNER, R ochester, N . Y.

RICHARD J . PLUNKETT, M-D-. Chicago, Managing E ditor

V olum e

5

1952

PUBLISHERS
■
AMERICAN MEDICAL ASSOCIATION
CHICAGO 10, ILL.

CONTENTS OF VOLUME 5
'

JA N U A R Y

19$Z, N U M B ER

1
PAGE

Treatment of Chronic P ulm onag Disease w ith ln tcrm itteu t Positive Pressure Breathing:
1 * tE ra lu a tlo n by Objective Physiological Measurements. H urley L. Motley, M.D.. and
M.D., Philadelphia............................................................................

1

Tetiyl Toxicity: A Summary o i T en Years’ Experience. Burton B. Bergman, M.D.,
Newark, N . J ................. ...................................................................................... ......................

10

JoSffT

Exhaust Ventilation for Machine Tools Used on M aterials of H igh Toxicity. H - F . Schulte,
M.S.; E . C. H yatt, B .S , and F . S. Smith J r , B .S , Los Alamos, N . M ex........ . ........... 21
Further Investigations on Chronic Cadmium Poisoning: A Study on Rabbits w ith‘Radioactive Cadmium, Lars Friberg, M D „ Stockholm, Sweden................................................... 30
Plastics: Their Dermatological and Chemical Aspects. George £ . Morris,
M D , B oston......................... ............................................................................... .......... .........

37

Effects of Dimethyl and Diethyl Paratdtrw hcnyl Thiophosptate on Experim m ial Animals.
W illiam B. Deichmann, P hD .} W ilfiam Pugliese, A.B., and James Cassidy, B .S ,
Albany, N, Y .......................................................... ..............,•................................................... 44
Physiological Response of Experimental Animals to the Vapor of 2-N itropropw e. Joseph
F, Treon, P h D , and F ran k R. Dntra, M.D., Cincinnati......................... .......................

52

The Spiral Sampler—A N ew Tool for Studying Particulate M atter. Charles D , Yaffe,
M .S.; Andrew D. Hosey, B .S , and John T . Chambers J r , B.S., Cincinnati................. 62
Management of the Older Employee with Medical Problems. Rufus Baker Crain, M.D.,
M .P.H ., Rochester, N . V . .........................................................................................................

71

Abstracts from Current Literature................................................................................................

82

News and Comment........................................ ..................................................................................

95

Book Reviews................................. ............................................................................... ..................

96

FEBR U A R Y

1952, N UM BER

2

CONFERENCE ON PROBLEMS OF NOISE IN INDUSTRY
Sound and Its Measurement Leo L . Baranek, D.Sc-, Cambridge, Mass.................................

97

Industrial Plant Environmental Study. Charles R. Williams. F h .D , Boston......................... 109
Estimating Percentage Loss of Hearing. H oward A. Carter, M .E , Chicago......................... 113
Noise Safety Criteria, K arl D. K ryter, P h D , Washington, D . C , . ................................. . . .. 1,17
E ar Lesions Caused by Acoustic Trauma. Stacy R. Guild, F h -D , Baltimore......................... 121
Clinical Aspects of the Problems of Noise m Industry. H ow ard F . House, M D , Los
Angeles ........................................... .......................................................................................... 124
Noise and Noise Reduction: Control.,Methods Applied. W entworth D. Boynton, B.Eng.,
’
Baltimore ...................................... ; ......... ...............................................................................
129
The Legal Aspects of Occupational Deafness. Noel S. Symons, B uffalo............................... J38
Medical and Legal Aspects of Noise in Industry: A Discussion of Papers Presented. Gordon
D. Hoople, M D , Syracuse, N . Y . . .................. ....................................................... ............. 157
Summary of Conference on Problems of Noise In Industry. W alter A . Kosenblith,
Ing.Rad-, Cambridge, M a s s . . . . . . . . . . . . .......................................................................... .
j®
HI

V

ÎV

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE

.

FEBRU ARY —Ctm/ftWid
PAdfi
Abstracts from Current L iterature......................... ......................................... .............................. 164
News and Comment........................................................ ..................................................................181
Book Reviews......... *...................... ................................................................. ............................. 183
M ARCH

1952, N UM BER

Hazards from Thernr
P h D .; J<*n D. i
ville, V a ...,.< * Man, Submarines, am
London, C om ...

3

PROCEEDINGS OF THE CANCER PREVENTION COMMITTEE

Patissier’s Oceup&tiot

Note and Index of Proceedings........................................... ...........................................................185

Disinfcetive Action «
Spores. Robert '
Dohrman H . By

Purpose and Program of the Cancer Prevention Committee. William E. Smith. M.D.,
New Y o rk ..................................... ............................................................................................. 187
T rends In Cancer Mortality. E, C urler Hammond, ScD ., New Y ork................... .......... .

190

Influenza-Virus Vac*

Lung Cancer in the Chromate Industry. Frederick Gregorius, M.D., New Y ork..................196

The Physician ia Im

U se of Life Insurance Company Records for Cancer Studies. E . A. Lew, A.M-, F.S.A.,
New Y ork..................... . . . . . . . . . .............................................................................................T 198

Some Colloidal Prop

Occupational Cancer H asards in American Industries. W . C. H neper, M.D., Betbesda, Md. 294

Concentrations of P i
C h.Et S e D .,1

L ung Cancer with Special Reference to Experimental Aspects. William E. Smith, M.D.,
• New Y o rk .......................................................................................................................... ..
209

Special Article:
Prophylactic A s

Studies on Lung Cancer in Relation to Smoking. Ernest L. Wynder, MJÛ., New Y o rk ........218

Abstracts from Cm

Industrial Exposure to Chromates in New York State. H erbert S. Dankman, New Y o rk .. 228
Use of the Cytologic Method in Industrial Medicine, with Special Reference to Tumors of
the L ung and the Bladder. H enry A. Cromwell, M.D., and George N. Papanicolaou,
M.D„ New Y ork.............................................. .......... ............................ ........ , ...................... 232
Bladder. Lesions from Aromatic Amines : Statistical Considerations and Prevention. Mario
Barsotti and Enrico C. vigliani, Milan, Italy. Translated by Louis J. Sciarini, Ph.D.,
New Haven, C o n n ............................ ............................................................................ .
234
Survey of Some Current British and European Studies of Occupational Tumor Problems.
W illiam E . Smith, M,D., New Y o r k . . . . . . . . . ................................................... .................242

I
I

1

Books .....................

Evaluating Effects
Air Force.—
. Audiometric Data I
M.D,, Chicago

Chemical Causes of Occupational Cancers: Aromatic Amines Acting on the Bladder. René
Truhaut, Paris, France. Translated by Rosamond de St, Phalle, New Y o rk ....................264

An Objective Met!
M.S., Chicago

W orkm en’s Compensation Insurance as a Source of Data on Tumors In Relation to Occu­
pation. R. N . Gray, M.D., H artford, C o n n . . . . . . . . ........................................................... 274

Progress Report w.
Hearing. H on

T he P rogram of the New York State Occupational Cancer Committee. May R. Mayers.
M .D , New Y ork..................................................... ................. .................... .
279

A Spot Test for
Etherington, E

The New Jersey Occupational Cancer Survey. Edwin D. Merrill, M .D , Milford, N. J ___ 284

Pulmonary Tako*
William E . Js

Comments On Occupational Cancer Surveys in the United States. W . C Huepcr. M D
Betbesda, M d....................... ....................................................................................................7 288
A bstracts from Current L iterature....................... ............................................ ........................... 290

Jet Impacto n for
Fh-D* and J.

News and Comment..................................................................................................., ...................

Problem of. Astbir

Book Reviews..................................................... ..........................................................................
A P R IL

1952. N U M B ER

305

4

Studies on the Toxicity and Skin Effects of Compounds Used in the Rubber and Plastics
industries ; L Accelerators, Activators, and Antioxidants. F. S. Mallette, Akron, Ohio,
and E . von Haam, M.D., Columbus, Ohio............................................................" ......... ' 31J
T oxW ty of Sulhiric Acld M k t to Guinea Pigs. M ary O. Amdur, Ph.D .; Ruben Z. Schulz.
M .D , and Philip Drinker, Ch.lL, Sc.D., Boston......................................................... . .7 318

A Comparison o f '
Lewis H . Bro
cation Unit, ,
Bellevue Hos
Abstracts from C
News nnd Comm
Books .................

CONTENTS OF VOLUME 5
ATFLL—Continued
_

'

.

*
rACE

„
, <riwn T hennal Decomposition of Motor-Insulaling Materials. Julios Semlroy Jr.,
H * 1 & 7 o l J ^ W n S j Z * . B e th e a , M d , and Grover C P itts, P h D , Charlottes- ^
vine, V a............................. .....................: ....................................................................................
Man, Submarines, and C arton Dioxide. Commander H arry J. Alvis (M C), U S. N-, Hew ^
London, Conn............................... ....................................................... .................................
Patissier’s Occupational Diseases. F. Ronehese, M.D., Providence, R. 1................................. 347
nsrinfcetlve Action o£ Methyl Bromide, Methanol, and Hydrogen Bromide 0« Anthrax
° Spores Robert W . Kolb, M .S .; Roy Schneiter, Ph-D .; E arl P . F % d , M.S., and
Dohrman H . Byers, M .S , Cincinnati.........................................................................................384
Influenza-Virus Vaccination in Industry. C. F . Yeager, M D ., Bridgeport, Conn............365
t h e Physician in Industry and the "Alcoholic” W orker. Leo J . W ade, M D ., New Y o rk .. 363
Some Colloidal Properties of In ert Dusts. R. F . Hounam, B-Sc., W antage, Berks, England 37S
Concentrations of Particulates Found in A ir. Melvin W . F irst, Sc.D,, and Philip Drinker,
C h i , S c D , Boston.........................................................................................
387
Special A rticle;
,
Prophylactic Aspects of the Mental Health of the Physically Disabled............................. 389
Abstracts from Current L iterature....................................................................................................395

4,3

Books ............
MAY

1952. N U M B ER

S

Evaluating Effects of Industrial Noise on Man. M ajor H orace 0 . Parrack, United States
A ir Force........... .......... ................................................................................................................ 415
Audiometric D ata Following Exposure to Low-Frequency-Centered Noise. E. J. Sehowalter,
M .D , Chicago................................................................................................................. ............. 430
An Objective Method of Classifying Industrial Noise Environments. Ralph M. McGrath,
M .S, C h icag o ...................................................................................................................... . • 4&
Progress Report of Committee: Revision of Procedure for Evaluating Percentage Loss of
Hearing. Howard A . Carter, M.E„ Chicago..................................................................... 445
A Spot T est for Estimating Concentrations of Boron Hydride Vapors in A ir. T . L.
Ethcrington, B.S., C h.E, and L. V . McCarty, P h D , Schenectady, N . Y ..................... 447
Pulmonary T akosis with Involvement of the Stomach and the H e a rt: Report of a Case.
William E . Jaques, M.D., and K urt Benlrschkc, M D , Boston........................................ 451
J e t lmpactors for Determining the P artide-S ire Distributions of Aerosols. W . E. Rsnz.
P h.D , and J . B, Wong, M .S , Urijana, III........ .......................................... ...................... 464
Problem of Asthma in Industry. W . C Spain, M .D , and V- J . Fontana, M .D , New Y ork 478
A Comparison of W orking and Nonworldng Cardiac Patients. Leonard J . Goldwater, M .D .;
Lewis H . Bronstein, M .D , Beatrice Kresky, M D , and the Staff of the W ork Classifi­
cation Unit, Adult Cardiac Dinlc, Third (N tw Y ork University) Medical Division,
Bellevue Hospital, New Y ork..................... *................................ ...................................... . 485
Abstracts from Current L iteratu re............................................ ............................... ...................490
News and Comment.................................................................... ............................... .514
Books ............. ........................ ......................................................... .......................................

516

vl

in d u s t r ia l

h y g ie n e
JU N E

ano

o c c u p a t io n a l

m e d ic in e

1952. N U M B E R 6
PAOS

A Rational Approach to Air-Pollution Legislation. George E. Best, B altim ore.................517
Deposition oi Siliceous Dust in the Lungs of the Inhabitants of the Saharan Regions.
Quest for a Suspected Industrial Carcinogen. Carrol S. Weil, M A ; H enry F . Smyth Jr.,
P h D ., Pittsburgh, and Thomas W /N a le , M.D., New Y ork............................................... S35
Organization and Operation of a Study of A ir Pollution in Relation to Experimental
Carcinogenesis. Paul Kotin. M .D , Los Angeles.................................................................... 548
Clinical Pulmonary Physiology; I. Evaluation of Function Impairment and Now Develop­
ments in Therapy of Chronic Pulmonary Disease, Hurley L . Motley, M D ., Philadelphia 554
V apor Toxicity of Tetrachloroethylene for Laboratory Animals and Human Subjects.
V. K . Rowe. M .S.; D. D, McColllster, B .S.: H . C. Spencer, P h D ,; & M. Adams,
P h D , and D. D- Irish, P h D , Midland, Mich.....................................................................566
T he Environmental Health Program of the United States Public H ealth Service. Mark
580
D . Hollis, C.E., Washington, D. C.
O bituaries:
S ir Leonard H ill....................

587

A bstracts from Current Literature

589

News and Comment.......................

605

\

pj:'
);

A. M . A.
A It C H I V B S

O F

Industrial Hygiene
(kenpationaì Medicine
E D IT O R IA L
'

BOARD

RH ItlF JDÄtttKßft. C hief Editor .

SS Shattuck Street, Boston IS
THEODORE F . HATCH, P»tt»bnr(|h
FENN B. POOLE, G lendale, C alif.

OSCAR A . SANDER, M ilwaukee
. WILUAM A . SAWYER, R ochester, N . Y.

FRANK FMNCJ, C incinnati

HERBERT E. STOK1KGER, C incinnati

JAMES H. STERNER, Rochester, N . Y.

Volume 6
1952

ru n u s h e r s
AMERICAN MEDICAL ASSOCIATION
CHICAGO 1«, ILL.

'■ ¿ \ ' **

'l

■
iv

' 1 v . * '* .'vi,,

• «•

v .i

•

'

'

'

; i ’v i - v

'

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEM§
■

A U G U S T —-Cfl«Kntt/rf

•

; 'i |

F atal Exposure to Methylene Chloride Vapor. Samuel Moskowita, Ch.E.. F Í
York) and H arry Shapiro, M.D., Now Rochelle, N . Y .........................

R u b in a * *

Instrum ents for M easuring Secondary Radiation, W illard W . V an Allen, B .Sc.fl

!>

•ÍV ,
.-IK*
1« ,
, y

Ifcjr

Wt\

■&1

Studies on Fat*
.

H ealth Program a t a Medical Center, J. B. Feldman, M .D , and M. D. Kass
Philadelphia ............................................................................ ................

•.1 vl'/
l

li.

™ ............................. ......................................................................................... ; - - - k
A crylonitrile: Spectrophotometric Determination, A cute Toxicity, a n d M eehT
Action. Heinrich Bricger, M .D.; F redric Rieders, Ph.D „ and W illiam AS
A.B., P h ilad elp h ia................. ..................................... .....................• •••

1*

Industrial Medicine and the.G roup Clinic—a Mutually Advantageous Relatonship
Spencer Felton, M.D., Oak Ridge, T e n n ..,........ ......................... ........................

tl
V
■V

Toxicity of Ethylene Dihromide Determined on Experimental Animals.' V . K . R o w ® |
H . C. Spencer, P h .D .; D. P . McCollister, B .S .; R. L. Hollingsworth, M.S., t u r n
- A dana, P h .D , Midland, Mich.............................. ..................................................... O ,

&
■w

Etiology
mcd. H of*

Acute 9 * ^ 5

Meigs. M .

Anticholinesterase Activity of Tributyl Phosphate. Jean Captain Sabine, M.D., and É r
N ew ton Hayes, P h -D , Los Alarm s, N . Í Í . ..................... .............................................^

<e

Si.¡

I

m

j« se n . »«•*
Ttmporary <3?
John B. u i

Chronic O ral ‘

Special Reports:
T hreshold Limit Values for 19S2............................................ . ............................ . —

Wilson

A bstracts from Current L i t e r a t u r e ...,,................ .................................... .

Abstracts fn

News and Comment........................................................................ ................

News a « l

cu
tí*"!

S E P T E M B E R 1952. N U M B E R 3
A ir Pollution by Hydrogen Sulfide in P o ra Rica, M exico: A n Evaluation of the Indd
o f New. 24, 1950. Louis C, McCabe, P h D ., and George D. Clayton, W ashington, O,

Femes and 1
Sven F*

Retention, Distribution, and Elimination of Inhaled Particulates with P articular Reference 1
the Evaluation of Radiologic Risk. M erril Eisenbud, New Y o rk .. .

Carbon Mo*
Alvls (

R apid Analytical Method for Air-Pollution Surveys: T he Determination of Total P a rti-.
culates and the Rapid Scmlqnantitativc Spectrographic Method of Analysis of the
M etallic Constituents in High-Volume Samples. R. G. Keenan, M.S., and D. H .
Byers, M. S , Cincinnati............................................................... ........

Industrial I
MD,

Studies on the Toxicity and Skin Effects of Compounds Used in the Rubber and Plastics
Industries,
'J
II , Plasticizers. F. S. Mallettc, P h D , Akron, Ohio, and E . von Haem, M .D ,
■•¡‘l
Columbus, Ohio ....................................................................................................................... 231-.

Occurrene
S. Lie

n i . Carcinogenicity of Carbon Black E xtracts, E . von Haam, M .D , Columbus, Ohio,
and F . S. Mallotte, P h D , Akron, O hio.............................................................................. 2 #

Counting o

.'>3

E ye H ealth Evaluation and Maintenance.
■'
A . D . Ruedemann, M .D , D etroit............................................................................................ 243
A rth u r K . Peterson, M .D , Chicago..................... ............................................. .......... .
248
Parathion Exposure and Cholinesterase Response of Quebec Apple Growers. Kingsley
Kay. M ,A , P h D .j L . Montanan, B A ; J . P . WtetBeh, B.Sc,; T . Doherty. Ottawa,
Canada; J . P aré, M.5c., and C Raclcot, Montreal, C an ad a.................................
252
Pharmacological Studies of Radiogermanium (GE*1) . Commander H . C. Dudley (M SC),
U . S. N , and lieutenant (Jg) E . J . W allace (M SC ), U- S, N . R ,.........................
263
A Rapid Micromethod for Electrometric Determination of Red Cell Cholinesterase Activity
in W hole Blood. W . E . MacDonald J r , Jacksonville, F la .; C, B- Pollard, and A. H .
Gropp, Gainesville, F la.......................................................... ................................................. 2/1
. A bstracts from Current L iteratu re........... ......................................... .............. ........................... 2 ^
News and Comment ............................................................ ............... ...................- ........................ ^
Books .....................................................................................................................................................292

i

Carbon T
Relative ’
C hid
Be

CONTENTS OF VOLUME 6

v

O C T O B E R 1932, N U M B ER 4
'

•

Submarine Rescue and Escape.

PAGE

Commander H a rry J, Alvis (M C), U . S. N ................. ,.2 9 3

« u-urinn of Sulfuric A d d M ist by H um an Subjects. M ary O. Amdur, Ph.D .; Leslie
^ S ilv e r m a n , SeD-, and Philip Drink«-, Ch.E., Sc.D., Boston................................................ 305
«
^

,i*. M a Five-Year Investigation of A ir Pollution in Cincinnati. J, Cholak, Ch,E-;
L j S e h a C B .S E ., and R. F . H o ff« , B.S., Cincinnati.................................................... 314

e«..Ain an F ate of Parathion in Rabbits, U sing Radioactive Isotope Techniques- J. A.
S j W , B &. ChJE.; W . F . Durham, PH.D., and G. W , Pearce, Ph.D., Savannah, Ga. 326
Temnorarv Changes hi Acuity of the Human E a r Following Exposure to Intense Noise.
T |S m B . Gallagher, M.A., and John K Goodwin, Ph.D„ Toronto, Canada.......... .
332
fftklottr of Corundum Smelter's Lung <Bauxite W orker’s Lnng, Shaver’s Disease), D r.
^ ^ m e d . H orst GSrtner, Saarbrucken, S aarland........................................................ - .............. 339
^

Carbon Monoxide Poisoning: A n Analysis of One H undred Five Cases, J. W ister
Meigs, M D , New Haven, C onn, and J. P . W . Hnghes, M .D , Birmingham, England. 344

Chronic Oral Toxicity of Chlordan to Rats. Lester Ingle, P h .D , Urbana, Hi........................ 3S7
Ahsorotion and Excretion of Inhaled Fluorides: F urther Observations. 0. H- Collings Jr.,
M jV M .P.H -: R. B. L. Fleming, M .S.; Roy May, M.S., and W . 0 . Bfancom, B .S ,
W ilson Dan» (Sheffield. P . 0 ) . A la........................................................................................ 368
Abstracts from Current L iterature................................................................................................374
News and Comment........................................................ ................................................................... 380
N O V E M B E R 1952. N U M B ER 5
Fumes and Gases in A rc W elding, E rik Thrysm, C h.E.; Gideon Gerhardsson, Ch.E., and
Sven Forssman, M .D , Stockholm, Sweden...........................................................................381
Carbon Monoxide Toxicity in Submarine O perations: Report of a Case, Commander H . J .
Ahris (M C), U . S. N ., and Chief Hospitaleorps Man G W . Tanner (S S ), U. S. N ... 404
Industrial Medicine in Sw eden: Recent Experiences and Future Problems. Sven Forssman,
M.D., Stockholm,. Sweden........................................................................................................ 407
Counting of D ust Particle« by Phase Microscopy. Germain Crossmon, B .S , Rochester, N . Y. 416
Occurrence of Anthrax Bacilli in the Carpet-W ool Industry in the United States. Robert
S. Lloyd, M .S , Cincinnati.................................................................... .................................. 421

Carbon Tetrachloride M ixtures in F ire Fighting. H . H . Fawcett, Schenectady, N . Y . . . . 435
Relative Toxicity of Lanthanum. Tantalum, and Thorium Compounds in the Developing
Chick Embryo. L. J. Mechlin, M .S .; P. B. Pearson, Ph.D.. and G A. Denton, B.S.,
Beltsville, M d . ........................................................................................................................... 441
Problems Encountered in Field U se c£ Thomas Autometer. Paul M , Clever, D etroit.......... 445
Obituaries:
.
Fenn Eugene Poole, M.D......................... ................................................................... ..............450
Abstracts from C urrent L iterature................... ........................................................................ ..

4S2

News and C om m en t...... ..................................... .................................................................... ........... 464
D EC EM B ER

1952. N U M B ER

6

Industrial H ealth Experiences in Pennsylvania.
How We Began the W ork. Charles-Francis Long, M.Dh Philadelphia................... ...

469

The T rade Organization Fosters In-P lant Industrial H ealth: T he Williamsport Experience.
C E , Noyes, WlUiamaport. P a . . , . . ...................................................... .................................. 472
The Union Health Center Fosters Employee H ealth : The Philadelphia Experience. Joseph
A, Langbord, U JD , P h ila d e lp h ia ................................... ....................................................... 474

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INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE

tf'i

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DECEMBER—Continued

'¿ i: ■.
1
«•i -?ir.
' '¿i.
r: :.vi; j
S’1
*=.. J .

T h e P ittsburgh Experience in Undergraduate and Graduate Industrial Medical E ducation^0.,
T . Lyle Hazlett. M J)^ P ittsburgh........, .............................................. ............7 .7 ^ 7 ™ '

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1 ^
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6*. 7)1.
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The Industrial Medical Association and Medical D irectors’ Club in Pittsburgh. Daniel c .
31
Braun, M.D., Pittsburgh.................................. ...................................................................... 77 4 7?^
Ttcbnfaua of Build-Up of Industrial H ealth in a. Single Community. John D. Harley.
‘‘
M.D., Williamsport, P a ........................................................................................................... , t ^ a

The Technique of die Build-Up of an Individual Industrial Medical Practice. Glenn Everts.
M D ., Philadelphia,................................................................................................. .............7 .7 :481

®

Improved Photometric Determination of Carbon Monoxide by M eans of Palladious Chloride.
' ■.
Eugene W . Rice, P h D ., O m aha..................................... ...................................................
qg
'.V.

II;'

U rinary E xcrrtlw i of Pa'ranitrophenol Following FaratM on Exposure. Jan Lieben, M .D.:
Rudolph K , Waldman, D r. Chem7 and Leonard Krause, M.S., H artford, C o n n .,,.... 49)

\

Coproporphyrinurta. Sherman S. Pinto, M.D., D enver; Christine Einert. M .D ; Wesley J.
Roberts, Ch.EL, Berkeley, C alif.; Grant S. W inn, P h .D , and K , W . Nelson, B .E i,
S alt Lake City.............. . . . . ; ............................................................................................. .777 496,

'

Retention of Air-Borne Particulates m the H oman L ung; I I I . H . D. LandahL P h.D .;
T . N . Tracewetl, B.S., and W . H . Lassen, B.S., Chicago................. ................................. 508

.
'

Bilateral Lenticular Opacities Occurring in a Technician O perating a Microwave Generator.
Frederic G. Hirsch, MJD.. and John T. Parker, M.D., Albuquerque, N .*M ex.,............512
Death A fter Repeated Exposures to Refrigerant Gases; Report of a Case. Joseph
Mendeloff, IL D ^ Fayetteville, N . C . . . . . ............................................................ .................518.
Short-Term Intraperitoneal Toxicity Tests. David W . Fassett, M.D., and Robert L.
Roudabush, Fh.D., Rochester, N . Y ................................................................. .
525
Chemical Alopecia; A Unique Case. George E . M orris, M.D., Boston.................................530
Correspondence:
'
Impairment of Pulmonary Function in Anthracosilicosw.
Prem ysl P etn if, Prague, Czechoslovakia.............................. ............................. ....... ............ SJ2
H urley L. Motley, PhJD., MJD., J-os Angeles............................... ........................... .............532
O bituaries;
H erbert George D yktor........................

534

Abstracts from Current L iterature.....................................................................................................S35
News and Comment......................................................................................................

554

Books ..................... .................. ......................................................................................................., , 555

(,

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A. M . A.
a

r

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Industrial Hygiene
and

Occupational Medicine
E D IT O R IA L

BOARD

PHILIP DRINKER, C hief Editor
$6 Sbattuek Street, B oston 15

RALPH C. LEGGO, Crockett, Cellf.

H. H. SCHRENK, Pittofturgh

FRANK PRINCI, ClncIniMtl

CHARLES F. SHOOK S it, Toledo

OSCAR A. SANDER, Milwaukee
JAMES H. STERNER, Rochester, N. Y.
HERBERT E. STOKlNGER, Cincinnati

V o lu m e 7
1953

PUBLISHERS
AMERICAN MEDICAL ASSOCIATION
CHICAGO 10, IL L .

CONTENTS OF VOEUME 7
-

JA N U A R Y

19S3. N U M B E R

1
PASS

A ir Sampling w ith Membrane Filters. Melv*n W . F irst, Sc.D.’, and Leslie Silverman, ScJX,
Boston
.........................................................................................................................

1

Occupational Skin Cancer in a Group of T a r W orkers. R. R. W . Fisher, M.B., B.CH-,
D .P.H ., D J .H „ London, England.............................................................................................

12

Behavior of M ercury in the Animal Organism Following Inhalation. W illiam F . Ashe,
M.D.J Edw ard J . Largent, B .A .; Frank R . Dutra, M J3 .; Donald M. Hubbard, Ch.E.,
and M orris Blackstonc, Cincinnati.......... ...................................................... .................... ..

19

Barltosis: R eport of a Case. Eugene P . Pendergrass, M.D., and Roy R. Greening, M.D.,
Philadelphia ................................................ .................................................................................. 44
Portable Electrostatic Precipitator Operating from 110 Volts A. C. or 6 V olts D . C,
Andrew D . Hosey, B.S., and H erbert H . Jones, B.S., Cincinnati................49
Notes on Preparation of D ust' Samples for Microscopic Siaing. Melvin W , F irst, Sc.D.,
Boston ................................. ............ ............................................................................................ 5$
T oxidty of 2,4-DichJorophenoxyacetic Acid and 2,4,5-Trichlorophenoxyacetlc A cid: A
R eport on T heir Acme and Chronic Toxicity in Dogs. Victor A . Drill, Ph-D,, M JD ,
and Tomiharu HJratrfea, M.D., D e t r o i t . . . . , . . . . . , . . , .................................................... 61
Abstracts from Current L iterature...................................................................................................

fig

News and Comment.................... .......................................................................................................

86

FEBR U A R Y

1953. N U M B F it 2

Historical Relations of Medicine and Engineering. W illiam S. McCann, M.D., Rochester,
N . Y ...................... ............................................................................. .......................................... 87
Urinary Excretion of Paranitrophenol Following Exposure to Parathion: Progress R eport
J a n Lieben, MJD.; Rudolph K . W aldman, D r. Chctn., attd Leonard K rause, M.S.,
H artford, Conn............. .................... ...................................................................
93
Antimony Poisoning In Industry. Lucian E . R e n « , M.S., Little Bock, A rk .........................

99

Small Radioactive Spheres for Possible U se in Medical or Biological Investigation. L. P .
H atch, S .M , Upton, L. I., N- Y ............. ....................................... .................................. . 109
Occupational H ealth Activities and Objectives of the W orld H ealth Organization, Milton
I . Reenter, MJX,
and Oswald*» L. D a Costa, M.D., Geneva, Switzerland.......... 1U
Toxicology and Safe H andling of CBP-55 (Technical 1-Chloro*3-Bromopropene-1). C H ,
.
H ine, M JD , P h ,D .; H . H . Anderson, M D .j H . D . Moon, MJD.; J . K. Kodama, B.A,j
M . Morse, B ü , San Francisco, and N . W . Jacobsen, B .S , Emeryville, Calif.......... llg
Use o f Calcium Ethylenediam inetetmcctatc in T reating Heavy-M etal Poisonings Report
of a Conference.Held at Massachusetts General H ospital..................... 137
U se of Calcium Ethylenediam inetetmcetate in Cases of Lead Intoxication. H , Foreman,
M .D , Los Alamos, N. M e*,; H , L. H ardy, M .D , Boston; T. L. Shipman, M,T>
L os Alamos, N . Mex., and E, L. Belknap, M .D , M ilw aukee...................................... 14g
Buscopan In Treatm ent of Experimental Poisoning by Parathion, Methyl Parathion, and
Systox. W illiam B, Deichmann, FhJD,, and Roman Rakoeay, Dipl. Ing. n ^ , Albany

N- Y........... ....................................................................... . ‘___

’ ieo

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE

iv

FEB R U A R Y —Continued

;

!

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FAOÎ

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Comparative Inhalation Toxicitica of Four H«logenated Hydrocarbons to R ats and Mice in
the Presence of Gasoline F ires: Carbon Tetrachloride, Monochloronionobromomethenc,
Difluorodibroroomethaoc, and Trifluororooftobromomethanc. Charles C Comstock
and F red W . Oberst, P h .D , Army Chemical Center, M d . . . , , ....................................... 157

tt

•

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A bstracts from Current L i t e r a t u r e . . . . . . . . . . . .......................................................... ................... 168
News and Com m ent.'................. ..................................... ................................. .... ..........................186
. M A R CH

1953. N U M B E R

187

Exposure of Connecticut Tobacco W orkers to Parathion. R. A. Schaefer, B.Cbcm., and
G. H . V a n « , B .S , H artford, C o t m . . . . . . . . ........................................... ................................ 193
Toxicological and Pharmacological Studies on Chlordano. Anthony M . Ambrose, P h .D .:
H erb ert £ . Christensen, M .S.; Dorothy J. Robbins, B.S., Albany. C alif, and L dland J.
R ather, M D , S an Francisco....................... ............. ......................................................... 197
Evaluation of Long-Term Radiation Exposures. Duncan A. Heladay, M .A , Salt Lake City 211
Agents Diminishing Skeletal Accumulation of Lead. Norman S. MacDonald, P h D .;
F lo rita E m irlia n . A .B .; Patricia Spain, A .B , and Donald E . Rounds, A .B , Los
Angeles .............................................................................................................. ............... .
217
Exam ination of H eat Stress Indices: Usefulness of Such Indices for Predicting Responses
of A frican Mine Laborers. C, H . Wyndham, M .B .; W . van der M erwe Bouwer. B.Sc.;
H . F . Paterson, B.Se., and M. G. Devine, B .S c, Johannesburg, Union of South .
A frica ..................................................................................................... ..........................
221
W orking Efficiency of Africans in H e a t: Effect of V arious Saturated A ir Temperatures,
W in d Velocities, and Rates of W ork. C- H . W yndham, M B .; W . van der Merwe
Bouwer, B .Sc.; H . F. Paterson. B.Sc., and M, G- Devine, B.Sc,, Johannesburg, Union
of South A f r i c a . . . ................................................................................................ . — . . . 234
Periodic H ealth Examinations- W . Leigh Cook J r , M .D , Pittsburgh........................... .

241

Improvements in the Rapid Screening Method for Lead in Urine. W . W , Woessner, P h .D ,
P enns Grove, N . J , and J. Cholak, C incinnati.......................................... .......... ................. 249
Correspondence:
A Rational Approach to Air-Pollution Legislation.
Thom as C W orts, Pittsburgh............................................................ ........... ......................... 2S5
George E , Bast, B altim ore................................................................ .............. ...................... 257 •
A bstracts from Current L iterature................................................................................................. 259.
Books

....................................................................................... ............ *...................... ...................... 274

.Medical Motion P ic tu re s ............................................■
A P R IL

.............. .............................................274

1953. N U M B E R

Kay, and J.
Acute Toxicity
Stoking«’. 1
Toxicity of B u t
Carl G Sr
Blood and U rio
Leo LaFrai

3

Industrial Hygiene in Britain. B, H . Harvey, M.A. (O xon.), Boston..................................

Observations on

4

E ditorials:
'
D eaths D uring the Severs F og In London and Environs, Dec. 5 to 9, 1952. Philip
D rinker, Boston.................................................. ..................................... ............................... 275

Planning a S t'
M ethodoloi

M .P .H ,
AntbracosiUco!
Correspoadenc

Statistical
A ctivity

John F . ■
D. O. H i
Obituaries; '
Paul A r
Abstract« frt
News and C

Distribution
P h D ., «
Design of a
Center.
Chollnestcn
InMCtiC
M.D.
Jane)

Survey at
W ashb
Procedure
Hump'
N e w M e tt
Readh
Dermatiti:
Georg
Space an*
L abor

277

Abstracts

Comparative Toxicity of Synthetic and N atural Glycerin, Charles H . Hinc, M D , P h D .:
Ham ilton H , Anderson, M D . j H enry D . Moon, M .D .; M ary K . Dunlap, D .V .M , and
M argarita S . Morse, B .S , San Francisco........................................... ............................... 282

News a n

Rapid Determination of Lead in Old U rine Samples. M ary O . Amdur, P h .D , Boston—

Books

.

CONTENTS OF VOLUME 7
A PR IL r~Cmime&

PACE

Observations on Toxicity of A ld rin : I. Growth and Estru* in Rats. W . L. B all; Kingsley
Kay, and ]■ W . Sinclair. Ottawa, Ont., Canada................................................................ . 292
Acute Toxicity of Carnotitc O re Dust. H erbert B. iJVllson, Rochester, N . Y .; H . E.
Stokinger, P h D ., Cinclnpati, and George E . Sylvester, Rochester, N, Y ............... .
301
Toxicity of Butyl Stearate. Dibutyl Sebacatc, Dibutyl Phthalate, and Methoxycthyl Oleate.
Carl C-. Smith, P h D , Cincinnati............................................................................................. 310
Blood and U rine Changes in Experimental Beryllium Poisoning. C h a rle s). Spiegl, Ph.D<;
Leo LaFrance, B.S., and Betty J. Ashworth, B .S , Rochester, N . Y ................................. - SI9
Planning a Study to Determine the Effect* of A ir Polution on H ealth: A Review of
Methodology. A rth u r F . W . Peart, M.D., D .P.H ., and Gordon H. Josie, M .S c,
326
M .P .H , Ottawa, O n t, Canada...................................................................
339
Anthracosilicosls O ccurring in a Foundry Employee. L. E , Hamlin, M.D., C hicago...
Correspondence:
.
Statistical Analysis of N orm al Human Red Blood Cells and Plasma Cholinesterase
Activity Values.
John F . M archand, M.D„ New Y ork....................... ............................... ........... ................
D. O- Hamblin, M .D , New Y o rk ....................................................................... .....................
Obituaries :
Paul Ardeen N eal, M.D.........

353

A bstracts from C urrent Literature

355

News and C o m m e n t...,..................

365

MAY

1953. N U M B E R

S

Distribution and Retention of C arrier-Free Rndloberyllium in the R at. C. D . Van Cleave,
Ph.D „ and C, T , K aylor, P h D , Chapel H ill, N . C . .............................................. ............. 367
Design of a New Five-Stage Cascade lmpactor. James D . W ilcox, B .S , Army Chemical
Center, M d ~ . . . ............................................................................................................................* 376
Cholinesterase Response and Symptomatology from Exposure to Organic Phosphorus
Insecticides. W . Taylor Sumerford, P h D , Wenatchee, W ash.; W ayland J . Hayes J r ,
M D , P h D , Savannah, G a.; J. Monte Johnston, M .D .; Kenneth W alker, B .S , and
Janet Spillane, B .S , Wenatchee, W ash....................................................................... .
383
Survey of Insecticide Spray Practices Used in- die F ru it Orchards of N orth Central
W ashington. Gordon S. Batchelor, M .S , Wenatchee, W a s h ........................................1. 399
Procedure for W eighing Fluted Filters with U se of Aluminum-Foil Envelopes. P a u l A.
Humphrey, S .B , and Daniel M. Morgan, B .E d , Idaho Falls« I d a h o . , . . 402
N ew Method fo r M onitoring A ir-Borne D u st P . F . H olt, P h D , and A. J . Chalk, B .S c,
Reading, E ngland........................................................................................... .............................494 •
D erm atitis from W a te r Glass: Caused by Synergistic Action with an Alkaline D etergent
George E . M orris, M D , Boston....................... ............................................. .........................411
Space and Labor-Saving Devices In the Industrial D ispensary: V II. Portable Clinical
Laboratory Equipment for Field Use. Jean Spencer Felton, M .D , Oak Ridge, T e n n ... 413
A bstracts from C urrent L ite ra tu re ........................ ............. ..........................................- .............422
N ew s and Comment............................................................................ ...................................... ..

451

Books

452

................ .................. ............................................................................... .................

{

vi

•

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE
JU N E 1953- N U M B E R 6

thVt
Effect of Modifications of the Surface of Q uarts on Its Fibrogcnle Properties in the Lungs
of R ats. E. J , K ing; G. P . Mohanty; G V- H arrison, London, England, and G. N agel'
schmidt, Sheffield, England............................................................ ............................ .
455
Acute Toxicity of Mineral Dusts. Jean C Dale, and E . J. King, London, E ngland............478
Adsorption of Dyes, Atnino Acids, Proteins, and Metal Hydroxides on. Q uarts. Jean C
Dale and E . J . King, London, E n g l a n d . . . . . . . .................................................. ................. 484
Field Equipment for the Collection and E ra l nation of Toxic and Radioactive Contaminants.
W . B. H arris; H- D. LeVine, and M. Eisenbud, New Y o rk ..................................... 490
Spwtroehemieal Analysis of Beryllium in Biological Tissue. Janus Y. E llc n W g , Oak
Ridge, Tenn., and Louis E. Owen, Lookland, O h io ,................................................................ 503
Radon Inhalation Studies In Rats. S. H. Cohn, P h D ., San Francisco; Lieutenant Com­
mander R, K . Skow (M .S.C.) U. S. N., and J . K . Gong, B.S., San F ra n c is c o ..,,........ 508

M

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the colle
been know» io
of the Biologic
commercially.
During the
published desc
bacteriology. T
A recent Ru»
and notes thal
Union.

Hyperthermic and Pathologic Effects of Electromagnetic Radiation (350 Me). lieu ten an t
Colonel John E Boysen, Medical Corps, United States A ir Force....................................... '516
Acute Narcotic Effects of Monochloromonobromomethane V apor In Rats. Charles C.
Comstock; Ralph W . Fogleman, D.V.M., and F red W . Oberst. Ph.D., Army Chemical
•
Center, Md, ................................................................................. ............................................. 326
Control of the Environment In the Prevention of Industrial Accidents. Bryan H - Harvey,
M.A. (O xon), Boston.................................................................................................................... 529
Abstracts from Current' L iterature..................................................................................................... 537
News and Comment............................ ........................................ .............................

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Method, Gis

A.
A H C H I V E S

OF

Industrial Hygiene
.

and

Occupational Medicine
E D IT O R IA L

BOARD

P IN U P DR1NKEH. CWef E ditor

55 SM ituck Street) Boetop 15
RALPH C- LEGCO, Croekett, C altr.

H . H . SCHRENK, P lttiD orgh

FRANK PHlNCI, c in e tn o iti

CHARLES F- SHOOK S r , Toledo

OSCAR A, SANDER, Mll-wau)<c*

JAKES H . STERNER. R ochester. N . T .

HERBERT E . STOKINGER, Cincfamatt

V olum e 8

1953

PUBLISHERS
AMERICAN MEDICAL ASSOCIATION
CHICAGO 10, ILL.

CONTENTS OF VOLUME 8
JU L Y

1953. N U M B E R 1
.
m *
Uwirlliosi» : Sw w nary and Survey of AB Clinical Types Observed in a Twelve-Year Period.
Joseph M . D eN ardi, t o
Lorain. Ohio; H . S. Van O rdstond, M D .; George H .
Curti», M .D , and John Zielinski, M D , Cleveland..............................................................
I
Industrial Hygiene in L atin America. John J. Bloomfield, B.S. In Eng., Washington, D . C ...

25

Noise and Audiometrìe H istories Resulting from Cotton Textile Operations. Jerome R.
Cox J r , S .M , Boston; Richard H . Mansur, M .S, Augusta, Maine, and Charles R.
Williams, Fh-D., Boston..................................................................... • • • • • .......................... 36
Nickel Poisoning ; I. Experim ental Study of the Effects of A cute and Subacute Exposure to
Nickel Carbonyl. J- F . Kincaid, P h D .; James S. Strong, P h D , and F . W illiam

Simderroan, M.D.. PhJD, Philadelphia................................................... : ................... 48
Plysfcal Medicine and Rehabilitation as Related to Industrial Health. F rank H . K rusen,
.
M .D , Rochester, M i n n . . . . . . . . . .............................................................................................. - 61
New Approaches to th e H ealth H a is rd Evaluation of Pesticides. Kingsley Kay, P h D ,
Ottawa, O n t, C anada......... ............................. .......................................................- .................

70

Obituaries:
Cyril T asker....................................... *..........................................................................................

76

Abstracts from C urrent L iterature....................................................................................................

78

News and C o m m e n t........................................................................................................

92

Books .......................................................................................................................................................... 95
A U G U ST

1953. N U M B E R

2

Role of the Physician in Labor Relations, B. A. Lindbcrg, Ailston, Mass.............................. ...

97

Challenge of Industry to the Medical Profession. W illiam H . Seymour, Boston...................... 102
Relationship Between the Piezoelectric Property and th e Fibrogenic Capacity of Lust.
Philip C. P ra tt, M D .; Donald Bailey; Anthony B. Delahant, and A rthur J. Vorwald,
M D ., Saranac Lake, N . Y . . . . . . . . . ........................... .......... .............................................. 109
Occurrence of Radon in Nonuranium Mines in Colorado. P . W . Jacoe, Denver........................118
Emanation of Radon in U ranium Mines and Control by Ventilation- E . C Tsivoglou,
P h D , and H , E . Ayer, B .S , S alt Lake City........................................................................... 125
Aggravation as a F acto r in Industrial Dermatitis. Bernard Appel, M D , Lynn, Mass........... 133
Nickel Carbonyl Poisoning: R eport of a Case. John L. Carmichael, M D , Birmingham, A la. 143
Kidney Injury A fter Chronic Exposure to Inorganic Mercury. Lara Friberg, M D , Tomteheda, Sweden; Sven HammarstrSm. M D , SnndsvaB, Sweden, and A ke NystrSm, M .D ,
Stockholm, Sweden........ ............................................................... ........................................ 149
Occupational H asards from Fungi Causing Deep Mycoses. Stanley S. Raphael, M R , and
Jan Schwarz, M D , Cincinnati........ ...................................................................................... 154
Cast of Panmyelophthisis A lter Exposure to Chtorophenothane and Benzene Hexachloride.
Lars Friberg, M .D , Tomtebods, Sweden, and Johan Martensson, M D , Lund, Sw eden.. 166
Toxicity of 2-Ethylhexyl Diphenyl Phosphate: I. Immediate Toxicity and Effects of Long­
Term Feeding Experiments. Joseph F . Treon, P h D .; Frank R. D utra. M D , and
Frank P . Cleveland, M .D , Cincinnati..................... .......................................... ................ 170
ili

iv

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE
'

A U G U ST— Continued
pace.

Fumes And Gâtes from Selenium Rectifiers Abused by Gross Overloading. Philip Drinker,
Ch-E., SeJD., Boston, and K . W ; Nelson, B.EcL, Salt Lake C ity.........................................
Abstracts from Current L iterature.................................................... ! ......... ...................................i$o
N ew t and Comment..............................................................................................................................2(R
Books

..................................................................................................................................................... 203.
SEPTEM BER

1933. N U M B E R

3

Chronic Bronchopulmonary Disease Due to Inhalation of Sulfuric Acid Fumes. Alfred
Goldman, M.D., and W illiam T . Hill, M D -, St, Louis.................................................... . 20$
Current Lines of Attack on the Smoke Problem in Britain. P eter C. G. Isaac, B.Sc.
(E ng.)i S.bL, A .M J.C .E., Newcastle upon Tyne, G reat B rita in .. . . . . . . . . . . . . . . . . . . 213
Chronic O ral Toxicity of Di(2-Etbythexyt) Phthalate for R ats, Guinea Pigs, and Dogs,
Charles P . Carpenter. P h .D .; C arrol S. W e ll M.A.. and H enry P . Sm yth Jr., P h.D ,
Pittsburgh ........................................................................................................... .................... 219
Tetrachlorethylene Exposure in a Small Industry, H . Robert Goler, M.D., M .P.H* and
227
H . R. Rossmiller, M.Dn Cleveland .......................................................................... ..
D ust Counting by the Most Probable Number Method. H arlow M. Chapman, B.S., Ch.E.,
Bethlehem, P a .................. .............................................................................................. ............234
Motivating Employees for Industrial Health. H erbert K. Abrams, M.D., Chicago............... 246
Physical Basis of H earing Damage and a Tentative Damage Risk Criterion for Steady-State
Noise. H ow ard G H ardy, P h D ., C hicago....................................................... ................... 250
Effect of Diet on the Susceptibility of the R at to Poisoning, by 2,4-Dinitrotoluene. Maurice
E . Shiis, SeD ., and Leonard J . Goldwatcr, M.D., New Y o rk .................................. ..........262
Toxicity of 2-Ethylhexyl Diphenyl Phosphate i
IL Metabolic F ate in M an and Animals. Joseph F . Treon, P h .D .; John Cappel, B.$.,
and H ow ard Sigmon, Cincinnati,.............. .....................................................................268
IIL Studies of tbc Extraction of Santkizer 141 from Polyvinyl Chloride Films by Food­
stuffs Under Various Conditions of Storage. J. Clark Koskie, M.$., St. L ouis.. . 281
IV . Skin Sensitization Studies of S antidser 141. Lawrence K . H alpern, M.D., and
Richard S- W d ss/M .D ., St. Louis.........................................................................
,2 8 4
Small Chamber fo r Studying T est Atmospheres. C J. Sptegi, P h D .; L. J . Leach. B.S.;
K , E Lauterbach, M A .; R. W ilson, B.S., and S , Laskin, B.S., Rochester, N , Y............. 286
Chronic O ral Toxicity of Ethyl Phthalyl Ethyl Glyeniata in R ats and Dogs. Harold G
Hodge, P L D .; E lliott A . Maynard, P h D .; H arvey J . Bianchet J r , M D .; Robert E
H yatt, M D ., Rochester, N . Y .; V erald K . Rowe, A.B., and H ow ard G Spencer,
P h D , Midland, MMi..............................
289
Special R eports:
Threshold Limit Values fo r 1953............ .......... ............. ........................................................ 296
O C TO B ER

1953. N U M B ER

4

Relationship Between the General Practitioner and the Industrial Physldan. E arl F . Lutz,
M.D* D etroit....................
299
Experimental Studies on Cancerigenesis o f Synthetic Liquid Fuels and Petroleum Substi­
tutes. W . C- Hueper, M.D., Bethesda, M d.............................................. ............................. 30?
Methyl Chloride Intoxication: Report o f Fifteen Cases. Howard Hansen, M .D.; N . K .
Weaver, M.D., and F. S, Venable, M.S., Baton Rouge, La............................................ ....... 328

CONTENTS OF VOLUME $
’

.,

v

O C T O B E R -^

TAGS
and H ta lth H azards of Boron H ydrides. Eugene H . Krackow, B A , Chemical

T° COW jo lte d S:[atei A rrny..........................................................................................................335
/wtnMikm?! Allergic Reactions Among W orkers in a Pcnicillln-M emiíacturing p la n t:
$taip|e and Inexpensive M ethod of Diagnosis and Treatment. A, Eaton Roberts, M.D„
.
-

Malvern, P a ..................................... ......................................................................................... 340
ct[on 0£ D iaiotirable M etabolites in M an A fter Aniline Exposure. David L, Hill, A.B.
Army Chemical Center, M d........................................................................................................ 347

Studies on the Toxicity and Mechanism of Action of Some N ew Insecticidal Thionopho.v
(hates. Kenneth P . DuBois, P h .D .; John Doull, P H D .; Jcre D troin, B A , and Oda K,
Cummings, M.S., C h ic a g o .................................. ........................................................ .
350
Applications of X-Ray D iffraction Analysis h i the Environmental Field. D . Lennox, B A „
a d J. Leroux, B A , O ttaw a, Q n t, Canada.............................................................................. 359
Toxicity Studies of Acetone Cyanohydrin and Ethylene Cyanohydrin. F . W illiam Sunderman, M.D., P h D , and John F . Kincaid, Ph.D ., Philadelphia............................................. 371
Toxicity and H azard of Dilsobotyl Ketone V apors. C. P. Carpenter, P h D .; U. C Poizanl,
M .S, and C S. W eil, M .A , P ittsb u rg h ................................................................................... 377
Semiportable Air-Sampling System. L. J , Leach, B .S.; R. H . Wilson, B .S.; K . E. Lautcrbach, M A ; C- J. Spiegl, P h D ., and S. Lasldn, B .S , Rochester, N . Y................................ 382
A ttra c ts from Current L iterature.................................................................................................. .. 334
News and Comment.............. ....................................................... ........................... ................389
Books .......................................................................................... *......................................................
NOV EM BER

1953. N U M B E R

390

5

Fear, Frustration, and F u tility: T h e'In d u strial Aspect. Rutherford T. Johnstone; M.D.,
Loe Angeles....................................................................................................................................391
Toxicity of Malathon; Sum m ary of Mammalian Investigations. Lloyd W . Hazleton, P h D ,
and Emily G. Holland, B .S , Fall* Church, V a ...................................................... .................399
Studies in Vanadium Toxicology: Reduction in the Cystine Content of R at H air. John T.
Mountain, M .S.; L ary l Lee Delker, B .S , and H . E . Stokingsr, P h D , Cincinnati......... 406
Absolute Method of Sampling and Measurement of Solid A ir-Borne Particulates; Combined
Use of the Molecular F ilte r Membrane and Electron Microscopy. David A Fraser,
B A Cincinnati................... ...................................................................'.......................
412
SHicotis In Mica Mining in Bihar, India. H arry Heimann, M.D., Washington, D . C,;
Samuel Moskowitz, Q lE , P h D , N ew Y o rk ; C. A H arihara Iyer, P h D .; M. N.
Gupta, M.B., D .I.H , and N . S. M ankiker, B .S c, B .E , New Delhi, In d ia ...................420
Some Physiological Effects of Disulfur Decafluoride (StFw) A fter Intravenous Injection in
Dogs: A Note on Its Toxicity to Rabbits. J: Palm er Saunders, P h D .; Milton Shoshkes,
M D ,; Michael R, De Carlo, P k D ., and Ernest C. Brown, M.D., Army Chemical
Center, M d....................................................
43d
Dust Sampler W hich Simulates U pper and Lower L ung Deposition. W . B. H arris and
Merril Eisenbud, New Y o rk ................................................... ........................................ ..
446
Bneumoeoniosis in the Tungsten.Carbide Tool Industry: Report of Three Cases. Charles W .
Miller, M .D .; M artin W . D a v is,.M D .; Alfred G oldm an,.M D , and John P . W yatt,
M.D., S t Louis..............................................
453.
Studies of the Acute and Chronic Toxicity of Germanium. lieu ten an t Commander George
Kosenfeld (M SC ), U .S .N , and Lieutenant (jg ) A J . W allace (M SC), U .S .N .R ,
Bethesda. Md.............................................................................................. ................................466

vi

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE
N O V EM BER —Cotil*tm«i

Arobi

Absence of T oxic Manifestations in W orkers Exposed to Chlordane. W alter C. Alvarez,;:«
MX)., and Samvel Hyman, MJX, Chicago..........................................................................
]£ K

P it:!

..

VOM»*

Abstracts from Current L iterature............................................................. ..............................
N ews and* Comment........................... . ............................................ • ................ - .......................... . 4 i|
Books ......................... ............. ........................... .......... ...............................................................
D EC EM B ER

»S3. NUM BER

6

A cute Inhalation Toxicity of Beryllium: IV . Beryllium Fluoride at Exposure Concentra­
tions of One and T en Milligrams per Cubic Meter. H erbert E . Stokinger, FH.D,;
Charles J. Spiegl, F h .D .; R obert E . R oot: Robert H . H all. P h .D .; Luvflle T. Stead­
man, P h .D .; Catherine A Stroud, M .T .; Jam es K . Scott, M .D ,; Frank A. Smith,
Ph.D., and Dwight E . Gardner, B A , Rochester, N. Y ................................. .
493^
Systematic Toxicological Analysis by Spectrophotometric M ethods:
I . Nonalkaloid al Organic Compounds. George W . Roche, M.S., and Harold. N.
W right, P h-D , Minneapolis........................................................................................... 507'■a
II . Alkaloidal Poisons. Eleanor Berman, M.S., and H arold N . W right, Ph.D,, Minne­
apolis ....................... ............................... ..................................................... ..

TX Nt
in f!

518 1 H

Pharmacological Studies of Radiogermanium (GeT1) : II. Inhalation of Dusts, Commander
H . C. Dudley (M S C ), U . S. N ................... .................... ............................ ............................ 528

f f l

N ote on Mien D ust Inbalation. H arry Hcimann. M,D„ Washington, D, C ; Samuel Mos­
kowitz, Ch.IL, P h .D , New Y ork; C. R . H arih ara Iyer, P h .D .; M . N . Gupta, M .B,
and N. S. Manldker, B .S c, B E ., New Delhi, India................ ........................... 531

1 9
''9
Connecticut Program for Safe Aerial Application of Pesticides. Jan J-ieben, M.D., Hartford,
9
Conn. ................................................................................................ ......................................... .. 533
'i jH
Vinyl P lastics: T heir Dermatological and Chemical Aspects. George E . M orris, M.D,,
S
Boston ............................................ ............................................................................. ............... 535
Synthetic R ubbers: T heir Chemistry and Dermatological Aspects. George E. Morris.
9
M JX, B o s to n ...................................................................... ................................................... .. 540
Neuroses and Compensation: Chronic Psychiatric Disorders Following In ju ry o r Stress in
Compensable Situations. I. Review of die Literature. Alex D. Pokoroy, M.D., and
Floy J . Moore, MX)., Houston, T exas........................................................ - .................. .. 547
Toxicity of Silica: I . Silica Solutions. Lester D. Scheel; E . Flcisher, and F . W . Klemperer.
Trudeau, N . Y .............................................................................................................................. 564
Fluctuations of Breath Radon In Subjects Seated a t Rest. E . J , Martin, M.D., and J . K. W .
Ferguson, M.D„ Toronto, C a n a d a ....................................................................- .............. 574
Serious Poisoning by H exachlorocydohexane: Clinical and Laboratory Observations on Five
Cases. E . Danopoulos; K Melisrinos, and G. Katsas, Athens, G reece....................... ... 582
Correspondence:
Kidney In ju ry A fter Chronic Exposure to Inorganic Mercury. Leonard J. Goldwater,
M.D„ N ew Y o r k ....................... ...................................................................................... . . .
Abstracts from Current L iteratu re.............................................................................. .................
Books .................................................. .............................................................................................

1
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A* IME* A*
a r c h i v e s

o f

Industrial Hygiene
and

Occupational Medicine
E D IT O R I A L

BOARD

PHILIP DRINKER, Chi»r Editor
IS Statinole S tm t. Boato» IS
CHRISTOPHER LUOGO. Crockett Colti.
ROBERT O’CONNOR. Restart
TRANS TRINCI, Cincinnati

OSCAR A, SANDER. Mllrmnlee#
H. » . SCHRENK. PltWjvrgh
CHARLES V- SHOOK SB* Toledo

HERBERT E. STOKINGRR, Cincinnati

JU L Y
VOLUME 10

1954
NUMBER

1

Section n
I ndex to A . M . A . Archives op Industrial H ygiene
and Occupation al M edicine
fimi th e P eriod
J anuary through J une, 1954

Publidied Monthly by

AMERICAN MEDICAL ASSOCIATION
» 5 NORTH DEARBORN STREET

*

CHICAGO ID, ILLINOIS

Entaied u Second d m Metter Tan. 4, is*«, at the Foetofllce at Chi*
«*■0, Under the Act <AKarch 3, 187?. Annual SnW lptton, R8.0Q

CO

N T I N T S
ô * U fb u d

A tU c le A

Studies of Phosphorus Intoxication

paos

Dorothy / . Buchanan, Ph.D.; Me* V. Sigal Jr., PhD,; C, S. Robinson, PhD,;
Katherine Pope, BS.; Mary Mlle» Ferguson, BS„ and John B. Thotniton, M.D.,
Nashville, Term. ............... . . . . ..................... ..........................................................................

1

Comparative Exchange o f Calcium, Leod, and Radioactive Lead in Dogs
/ , Alfred Calhoun, MD.; Regina McLean, A.B.; 1, Cramer Hudson, PhD., and Joseph
C. Aub, MD., Boston........................................«........................................... . . . . . . . . . . .

9

Participation o f a Labor Union in the Study of Problems of Psychiatry in Industry

Louis L, Tunen, MU., St. Louis. . . ...................................... - ............ .................... . ...........

23

Toxicity of Silica

Lester D, Scheel, PhD.! B. Smith, BS.; J. Van Riper, BS., and E, Fleisher, 8S„
Trudeau, H. V. . ................... . . . . . . ......... . . . . . . .............................. .........................

29

Physiological Responses to Parathion Exposure

Rudolph K, Waldman, Dr. Chetn.; Jan Lieben, MD., and Leonard Krause, MDV
Hartford, Cam....................................... ................................................ ............................... .. 37
Comparative Toxicity of Two Vinyl-Substituted Phosphates
3 i

\ i

*\

5!
!!
;

j
j
j . __

lyre K. Kodam; Margarita S, Morse; Hamilton H. Anderson-Mary K. Dunlap, and
Charles H. M m , San Francisco........ ............................................... ............................... .. 45
Two Chambers for Use in Exposing Laboratory Animals to the Inhalation
of Aerosols

Edward C. J, Urban,

Saronae Lake, N. Y ,......................................................... .

Efficiency Studies o f the Electrostatic Precipitator

Kenneth E. Lauterboch, MA.; Thoms T. Mercer, MA.; A lasfair D. Hayes. MA..
and Paul E. Morrow,PhD., Rochester, if. ¥ .. .............................................................

}

j

62

69

.

fa fu la *

S je p & U m e n U

j Pj>A bitrqcts from Current L iteratu re.......................................................................... . t 76
i ft- News and Com m ent............
IT -

I C
i>

........................................................................................................

86

CONTENTS

O riginal A rlk lè t
Polonium in Uri"« of Miners Exposed to Radon

rAQ®

fo r y S u ilser, M S . , m d Joh n B . H u n k , P h D ., ¡Rochester, N , Y . ...........- ....................

89

Industrial and Laboratory Evaluation of a Silicone Protective Cream

R aym ond R . S u t k M , M D ., Cincinnati ......................................................................... 101
Migration of Inorganic Salts in Bone as Measured By Radioactive Lead
and by Alizarin

R egina M cLean, A D : ; J . A lfred C a lh o m , M D „ and Joseph C, A n b , M D ., B oston

113

Skin Penetration by Diamines of th e Benzidine Group

I.

W itte r M eigs, M D .; L ends J. Sciorini, P h D * M m H aven,. C o m ., an d W a iter A .

Van Sandt, MDMV Berkeley, Calif............................ ........................................ .

122

Executive Health Programs

George X . Somders, MD., New York........ ............................... ..................................... ..

133

Studies on Phosphorus Intoxication

Max V. Sigal Jr* PhD.; Dorothy J. Buchanan, PhD., and C. S . Robhuon, Ph.t).,
Noshvifle, Tern ............................. ................................ .........................................................142
Dilemma of Official Health Agencies as to Court Appearance

William G. Predrick, ScD.. Detroit................................................ ........................................ 148
inatte Hydrocarbons

■

J * .

I. fivtenc« in the Lat Angele« Atmosphere and the Carcinogenicity of Atmospheric Extracts
Paul K otin , M D .; H ans L F o lk, P h D .; P an i M oder, P h D ., and M a rilyn T hom as,
B A * L o s A tig e te t ................................... ................................................................... 1S3

II. Fresence la the Fortkaiate Phase of Gowline-Englne Exhausts end the
Cerchwgenkity of Eschenst Extracts
P aid K otin, M D .; H o n s L . F a lk, P h D , an d M arilyn T hom as, B A * L o t A n g ele s . . . . 164
Regular Deportments
Abstracts from Current Literature............................................................. ................... 178
News and Com m ent....... .................................................................................................... 182

TABLE

OF

k

CONTI

O R IG IN A L A R T IC L E S
Public Health Aspects of Atomic Power Development

Shields Warm, M.D., Boston...................................•....... ............ ................. 183
^

-Aouearance of Carcinoma Following Single Exposure to o Refrigeration
* PP Ammonia-Oil Mixture

uirhAfl B Shimhtn, M X,: A. A. de Lortmkr, MX).; J. Russell Mitchell, MX., and.
Son Francisco........................................................................ 186

%

Silicone Protective Creams

George & Morris, MX., Boston............................................ . ......... ................................... 194
Toxicology of Hydrazine

Stephen Krop, PhX., Army Chemical Center. Md............................................................ 199
lead and Coproporphyrin Excretion of Patients Treated with EDTA

Beniamin F . W. Ruofolo, MX)., and Hem* B, Enins, Ph.D., Boston..........................205
Irritating and Sensitizing Effects of Two Polymeric Plasticizers

F. William Sunderman, N X ., PhD., Philadelphia, tend Harvey B. Haag, M.D., Rich­
210
mond, Va.................................................................... ......................*............................ ..
^ t ô o l y s e c of Biological M aterials as Indices of Exposure to Organic
^
Solvents

212

Hetvey B. Elhint, PhJ)., Boston.........................................................................
^R esp o n se of Rats to Repeated Inhalation of Ethylènediamine Vapors

U, C. Possorn, MS., and C. P. Carpenter, PhJ)., Pittsburgh.........................
Toxicological Studies on p-Tertiary-Butyltoluene

223

'

S P E C IA L R E P O R T S
Interim Report on Air Pollution
'

A, T. Rossano Jrv Boston..................... .........................

Air Pollution and the London Fog of December, 1952

PftBip Drinker, Boston...............................................................

247

Third International Conference of Experts on Pneumoconiosis. Sydney,
Australia, 1950

Philip Drinker, Boston...............................................................................................
REG U LAR D E P A R TM E N TS
Abstracts from Current Literature
Hew* ond Comment........................

249

TABLE OF contents
O R IG IN A L A R T IC L E S
Deposition of Wind-Boma Particles on Human Skin

*; °E

CabrUlU A w l, MA„ and Doris Pury, BA., A m y Chemical Center, Md........273
Some Reactions Between Inert Dusts and Proteins

R. F- Hounam, BjSc., A. Inti. P., Wantage, Berks, England.................................284
Statistical Control of Fluorescent Particle Tracer Studies

F, R. Holden, PhD.; F. W. Drtseh, PhD., and R.D. Codie, Ph.D., Stanford, Calif.,. 291
Foundry W orkers' Pneumoconiosis in Switzerland (Anthracosilicosis)

/. R. RHilner, MD., Zurich, Switterland............................................................... 297
Observations on Toxicity of Aldrin

•

•

M, Crtoier, MAc.; IV. L. Ball, Ph.D., and Kingsley Kay, PhD., Ottawa, Canada— 306
Effect of Cortisone on Experimental Silicosis in Rots

Bruno Marenghi, MD., and Lorensa Rota, MD-, Milan, Italy......... . . . . ................ 315
Colorimetric Method for Determination of Red Blood Ceil Cholinesterase
Activity* in Whole Blood

Joseph H. Fleithtr, MA.PM., and Eleanor J. Pope, AM., Army Chemieol Center, Md., 323
C O RRESPO N D EN C E
Redon Inhalation Studies in Rats

Sidney Rust, London, England.................................................................
333
Stanton H, Cohn, San Francisco................ . ............................... ....................... 335
%
REG U LAR D EPARTM EN TS
Abstracts from Current L iterature........................................................

335

Hews and Comment..............................

359

table

of

contents

O R IG IN A L A R T IC L E S

SAGE

C h « t Rocntgenogrophic Study of Employees in a Large Pharmaceutical P lant •

W.G. C. Mxmrae, M.D., Pomona, N, Y............. .......................................••*-*......... .

361

Ozone Toxicity

Herbert & Stikinger, PhD., Ctn^wnoK...................................................................................366
. Occupational Arsenic Poisoning

May R. Mvytrs, MD„ Neva Yarh.......................................................... ............................-• 384
Tone and Fibrosing Action of Submicroscopic Particles of Amorphous Silica

A. Policafd, MJ>., PhD., ant A. CaUrt, M.D., Parti.........................................................

389

Bromethymoi Blue Screening Test
• J, H. Woifiie, MS)., and G. D. Winter, BS., Linden, N .J .................................................. 396

Endocrine Functions in Silicotics

Jifi VwkoW, MJD^ Bma, CMchoAevahia.. . . . . . . . ...........................

402

Studies in Vanadium Toxicology

N . A, Talvitu, BS., and W. D , Wagner, BS., Chuinnoti................................................ 414
REGULAR D E P A R TM E N TS
Abstracts from Current L iteratu re............................................ ........ ...........................423
News ond C om m ent........................................................ .......................... ......................445

v'
1

T A B L E

O F

j p

»*i '

C C f N T f e k M - i '>

•• x
'/

^
'

.

\

*

J
;

E D IT O R IA L S \ ? / ' T
fxperim entol L«ng Cancer

'

*"

ARTHUV- “
PA0*

D rin ker ..................... •............................ *.................... 449

#<,J>/rt JS. Hr*«“'* an<i

O R IG IN A L A R T IC L E S
W o rk m e n 's Compensation Under the Federal Laws
M orion* IV. G r ig s H C h i c a g o . .. : . : . . . ............................. .......................................... 451
Muscle Spasm in M anual Laborers

A M illunen, M .A .; M . I . K am on en, P h J )., M 3 . ; J. K tklberg, M .A ., and R . L a m iniitpfô, M A ., H e lsin k i ............................................................................. -•.................476
Microscopic Observations Correlating Tonicity of Beryllium Oxide
with Crystal Structuré

(!. C. C n n * « * , B S .,a n d IV . C. V andeM arh. B S V R ochester, N . Y ........................... 481
Carcinogenic Studies on Adsorbates of Industrially Polluted Raw and
Finished W ater Supplies
.

IV. C. fiuepcr, M J>„ Beihesda, M d., and C. C. R uchhoft, BJ>, Cincinnati............ .

•

488

Some Practical Aspects of Industrial Noise Measurement

Bottai. }

'

Louis /. P r o d s Jr., S 3 . , H artford, C onn. ................... ............................................ 496
Adsorption of Protein on Silica Surfaces

.

P, P. M olt and J. E . L . B ow eoti, R eading. E n g la n d .. ............................................ .
Dermatitis from W ateriest Hand Cleaners

503

.

George E. M orris, M .D ., B oston .................................................................................... 507
ï

Toxicology of Mono*, Di-, and Tri-Propylene Glycol Methyl Ethers
• V, K . R ow e, M 3 .; D , D . M eCollister, B 3 , ; H , C . Spencer, PhJ> .; P . O yen; R , L . .
H ollingsworth, M 3 ., M idland, M ich., and V , A . D rill, Ph.D -, M .D .. D etro it ..............509
Problem Drinking in Industry

Thomas H , H ogshead, M 3 . , W tim in g ion, D eL ........., ....... . ............... .................

526

S P E C IA L R E P O R T S

m m *.

'

Threshold Limit Yalues for 1954.................................. ............................................... 530

REG U LAR D E P A R TM E N TS
1

Hews and Comment................................................. ............................. .............. ........... 535

...................................................................... ; ..........................................536

I T 11
I
*•1 f4

table

of

o r ig in a l

contents

a r t ic l e s

FACE

Meteorology I" Air-Pollution Engineering

Canto» B> BAl **•> KS-i ^ m r Robintm,. MS-, and Pale S , Hutchison, B.S., Stan- ^
/¿rtf, Ckif.
........................................................................... *........... .............................. 1

physical Rehabilitation and Reemployment of the Handicapped
11

Frank H. &»#», MP., Rochester, Mi»»......................................................................
Industrial Air-Sampling for Anthrax Bacteria

Morris A . Gordon, PhD.; Max D. Moody, PhP.; Arm M. Barton, BS„ and Frank M.
Boyd. M.S., Atlanta.......................................... .................. - ..............................................
16
Mineral Content of the Lungs After Exposure to Asbestos Dust

F. Knox. MP., and / . Beattie, UP.. Rochdale, England.. ...............................................23

Distribution of Mineral Particles ond fibers in the Lung After Exposure
to Asbestos Dust

.

j,F. Knox, M.B., and J. Beattie, MP,, Rochdale, England...............................................

30

Botch Processing of Film for Radiation Protection of Personnel

R. J. MagUl, Berkeley. Calif......................................... . ..................................................

37

"Why Doesn't the W orker's Skin Clear Up?"

George B. Morris, MP.r Boston.. . . ........................... ...........................................................>- 43
Problems of Health in th e M arketing of Chemicals

.

V. K. Rowe, MS^ and E. M. Admte, PhD., Midland, Mich.............................................

SO

Radon Levels Found in Mines m New York State

Saul J. Harris, BSn Hew York................................................................................................

54

Range-Finding Toxicity D ata

Henry P. Smyth Jr„ PhP.; Charles P. Carpenter, PhD.; Carrot S . Weil, MP.,, and
Uroano C. Potzani, MS* Pittsburgh,....................... ... . .....................................................61
Gas-Mask Protection Against Decaborano

.

Wiltim FT. HU!, PAD., and J. L. Svkbriy, PhD., PUtsburgk.........................................

69

SPECIAL ARTICLES
Renew of Literature on Health Hazards of M etals

Sherman S. PMo, MD., Denver............... .......................... ...........................................
.

REGULAR DEPARTMENTS

77

.

Abstracts from Current L iteratu re................... ...............................................................79
Hews ond Comment............................................................ ............ ............ .
Books

87

table

of

contents

ORIGINAL ARTICLES
•

FACS

Smdy of Five Years of Employee Counseling in an Industrial Medical Program

Hanld A. Vomchen, MD.; Joseph M. Mason, MS., and Milton H. Kronenberg,
MD„ Peoria, III.......................................

.
91

Pulmonary Penetration of Particles Administered by Intratracheal Insufflation

tiervw Cmber, MS,; Theodore F. Hdteh, S.M.; Joseph A. Watson, MS., and
Thoms B, Gmcci, BS., Pittsburgh.....................................
124
/T richloroethylene and Dichloroethylene Poisoning

Robert $. MrBtmeg, MD., Flushing, ft. Y ........................... ...........................................

130

/T richloroethylene Toxicity

Morris Kleinfekt, M.D., and Irving R. Tabershaw, MD., Nevi York................................. 134
Hoelth Howards In Tunnel Construction

George L. Wilson, B S , and Harvey J. Roberts, BS., Charleston, W. Va....................... 142
/ D i r e c t Field Determination of Lead in Air

Mary 0, Atndur, PhD., and Leslie Silverman, ScD., Boston............................................. 152
Problems in the Study of Decaborane and Possible Therapy of Its Poisoning

Versa V. Cole, PhD „ MD.; David L. Hill, AD., and AHi H. Oikemus, Army Chemical
Center, M i .......... .................................... .................................................... .......................
IS®
Acute and Subacute Toxicity of Cyclethrin

C. P. Carpenter, PhD.; C, S. Wed, MA.; V. C. Possenti, M.S., and H. F. Smyth Jr4
PhD., Pittsburgh...... ................................................................................................................ 1<>2
REGULAR DEPARTMENTS
Abstracts from Current Literature

.........................................................................l $9

"News and Comment................................................................................... .................... 181
Books

181

table

of

contents

ORIGINAL ARTICLES
PAOS

Polarographie Determination of Lead in Blood
•

AusuoU» m n i e r , M.S. (Stockholm), and Carl-Eric HolmqiHsl, Chm. Eng. (StockM m h M J. (Harvard), Tomteboda, Sweden...................................................................... 183

Erythrocytic Inclusion Bodies in tho Blood of Chemical Workers
Janm P. Hughes, MD., and Joseph F. Treon, Ph.D,, Cincinnati....................................... 192
ifteosuremertt of Air Pollution .
i / :

J. Cholok, a j , Cincinnati, .......................................................................................................203

v-fojclcity Studies of Cobalt Carbonyls

JohH p Kincaid, PhD.; Jam** S. Strong, PhD., and P, Wüliom Sunderman, MD
Ph.D\ Philadelphia.............................................................. .................................................... 210

^

Inhalation Toxicology of Tetranitrom ethane
.

Henry / . Horn, MD., Fails Church, Fa........................................................................ .......... 213
Sickness Absentee Rate in Younger and Older Workers in a Small
M anufacturing Plant
.

Guy H. Fish MD„ Montreal, Canada................................................................................

223

Experimental Administration of Ertiylenediamme-Tetreacetic Acid in
Plutonium Poisoning
.

Herrs Foreman. MD- Los Alamos, H. M.; Philip A. Fuqua, MD., and William D.
Norwood, M.D.., Richland, Wash........................................................................................... 220
Berylliosis
if. S. Fan Orddnmd, MD., Cleveland............................................................................... . *• 232

Medical Service Program of th e Sidney Hillman Health Center of New York

Morris Brand, MD., Hew York............. ............- ................................................................... 235
SCIENTIFIC EXHIBITS
Rehabilitation of Spinal Cord ln)aries

.

W. Scott Allan, Boston.............................................. . . ................. ...........................................248
correspondence

■ | / /SHicone Protective Creams: A Clinical Study

.

C. C. Currie, Midland, Mich..................................................... . ...................................254
George E, Morris, MD^ Boston................. ............................... . .................... ............... 254
r e g u la r

d epar tm en ts

Abstracts from Current Literature.......... ........................................... ........................... 257
News and Comment............................................................................................................270
Books

TABLE OF CONTENTS
:

o r ig in a l

a r t ic l e s

PAGE

Protection from A ircraft Noise
. 273

Major Horace 0. Parrack, United State* Air Force... ■
investigation of Air Pollution

. 288

Paul Kotin, MX)., Lot Angeles............... - ......................
Benign Tin Oxide Pneumoconiosis

.

Georg* £ • Spencer, M .D ^ and W illiam C. W yeo ff, M X )., P ittsb urgh .......................... 29$
Acute Toxicity Studies of Decaborane and Pentaborane by inhalation

I . L. Svtrb ely, PhX>„ P i tt s b u r g h ..,.. ...................... ................................. .................298
Subacute Toxicity of Decaborane and Pentaborane Yapors

J. L. Svkbely, PhJ)., Pittsburgh................................ ..................................... 30$
Treatment of Organic Lead (Tetraethyl) Intoxication with Edathamil
Calciuipt«Disodiam

Karl V. KitsmEler, MX).; Jacob Cholak, Ch.E., and Robert A. Kehoe, M.D., Cin­
cinnati .......................-..................................................... .................... 312
Inhalation Toxicity of Ninety Per Cent Hydrogen Peroxide Vapor

Fred W. Oberst, Ph.D.; Charles C. Comstock, B£„ and Ethel B. Hockley, M.S.,*ecifh
the Technical Assistance of Lorraine Lawson, BS-, and Earle Greene, Army Chemi­
cal Center, M d. ....................................................................................... 319
X'Radiation from Electronic Power Tubes

S.

C. Ballard, Boston.................................................................................. 328

Hematological Investigation on Workers Exposed to Manganese Dust

Branko Kcsii, MX)., and Vera HSuslcr, DXf., Zagreb, Croatia, Yugoslavia.............. 336
D. D. T. Intoxication In a Family of Southern Taiwan

H. C. Hsieh, MX)., CVaa-Chow, Ping-Tong, Taman (Formosa)............................ 344
REGULAR DEPARTAMENTS
Abstracts from Current L i t e r a t u r e .......................... ..................................................347

TABLE OF CONTENTS
ORIGINAL ARTICLES
Ventilation of Uranium Mines

E, c Tsivogfou, PkD., Cindnnati, and H. E. Auer, B.S., Salt Lake City,
Atmospheric Monitoring for Alpha Emitters Using Molecular Filter Membranes

Thomas T. Mercer, BA., Seattle
Portable Electrostatic Dust Sampler with Electronic Air Flow
2?, G, Beadle; P. H. Kino,-and P, J. Blignout, Johannesburg, Transvaal, Union of

South Africa.................................................................................♦ ........................................... 381

induction with Surgical Talc and Transplantation of Granulation Tissue in
Cheek Poach o f Golden Hamster

George R. Bernard, PhD,; Donald I. Pall, Ph.D., and Rojendra G. Desai, M.D., Boston 390
Occupational Fractures Among Civilian Employees a t a United States
Naval Shipyard .
'

Warren R, Guild, MD., Boston,..,................. . .............................. .......................................397
Hew Environmental Respiratory Disease (Yokohama Asthma)

'

Lieutenant Cohmel Tyrem E. Huber; Major Sheldon W. Joseph; Major Edward Knoblock. Medical Corps, United States Army; Lieutenant PaulL. Redfeam, Medical
Sendee Corps, United States Army, a n d James A. Karakawa. Washington, D iC .... 399
Toxicity of the Oxides of Nitrogen
L Introduction mid Apparatus

Edward Le B. Gray, PhD,; Stanley B. Goldberg, BA., and Francis M. Patton, BS„
Army Chemical Center, MS.....................................................................................................409
II. A n ti InliafaHsu Toxicity of Nitrogen Dioxide, Rod Faming Nitric Acid, and White Fuming
Nitric Arid

Edward Le B. Gray, PhD,; Francis M. Potion, BS.; Stanley B. Goldberg, BA., and
Eara Kaplan, B.S., Army Chemical Center, Md........... ..........................................................418
lU. effect of Chronic Expoeure to Low Concontratienx of Vapors from Red Fuming Nitric Add
E>‘ ‘ ’ " ~
~ Stanley B. Goldberg, B A , and Francis M. Patton, BS.,

SCIENTIFIC EXHIBITS
Accident Syndrome—A Clinical Approach

Morris S. Schulcinger, MD., Cincinnali,...........................

...4 2 6

REGULAR DEPARTMENTS
Abstracts from Current Literature

434 .

News and Com m ent......................

452

/

1
K'i

TABLE OF CONTENTS
-

ORIGINAL ARTICLES

Iffcets of Inhalation of Low Concentrations o f Sulfur Dioxide upon
Man and O ther Mammals

page

Istfof Greemaald, PhD., New Y o r k . . .............................................. ................ 435
Inhalation Toxicity of Hydrazine Vapor

Charles C. Comstock; Lorraine H. Ltmoti; Earle A. Greene, and Fred W. Obertf,
PhD., Army Chemical Center, Md.................« . . . .............................................................
Treatment of Lead Colic with Cortisone and Corticotropin

Enrico C. Figlieni, Milan............................................. ....................................................

491

Food Usage a n d Food Habits of Older Workers

Charlotte M, Yomg, PhD.; Gordon F. Streib, PhD^ and Betty Jean Greer, M.NS.,
Ithaca, N. .. .................................................................................................................................. SOI
Foundry W orkers' Pneumoconiosis

O.

A . Sa n d er, M D ., M ilw a u k ee....... .......................................... .............................512

Health Hazards Involved in Use of Parathion in Fruit Orchards of
North C entral W ashington

Gordon S. Batchelor, MS., and Kenneth C. Walker, BS., Wenatchee. Wash............... 322
Treatment of Inorganic Lead Poisoning with Edothamil Calcium-Disodium

Elston L. Belknap, MD., and Margaret C. Perry, BA., MA., Milwaukee................. S30
OBITUARIES
James Stevens Simmons, M.D..............................................

548

REGULAR DEPARTMENTS
Abstracts from Current Literature....................................................

$50

Hews and Comment.................... .................................... - .............................. . ............. 538

A . M . A.
A R C H I V E S

OF

Industrial Health

E D IT O R IA L

BOARD

PHILIP HRJNKBR. CWaf Editor
55 SMrttw* Street, Boston IS
CHRISTOPHER LEGGO, Crockett. Calli.

OSCA» A. SANBEfi, Milwaukee

ROBERT O’CONNOR, Boato»

H . H . SCHRENK, Plttefcargh

CARL M. PETERSON, CMeego

CHARLES F . SHOOK, Toledo

■FRANK PR1NC1, Cincinnati

HERBERT E. STOK1NGER, Clnotnnntl

AUSTIN SUITS, Editor, A. M, A, Bclrettflc Publications
GILBERT S. COOPER, Mantel air Editor, Bpoolaltj Journal»

Vo l u m e 11

1985

PUBLISHERS ,
AMERICAN MEDICAL ASSOCIATION
CHICAGO 10, DLL.

SUBJECT

INDEX

TO

VOLUME

11

Thi following Index contain» an alphabetical list of significant subject» presented »a this
,
¿ ^ tra c ts are »«dexed by category under the heading “A n s m c i s . '’ Books reviewed
V<"T«i«t alphabetically by title under the heading "B ooks." Obituaries and death notiees are
^iated under the heading “D eaths,"

Absenteeism: sickness,
* 2 8 5 » and .their preventjon; protective eijuiprocnt,
44ft
determination of Eir-bomc
contaminants, S4, 266, 354,
44ft $36
-

Asbestosis—Continued
roentgenologic aspects, 189
scientific exhibits, 165
Atomic energy: personal pro­
tection in atomic industry,
42
B

B ooks —Continued
Pneumoconiosis Abstracts,
Vol. 2 (Middleton, ed.),
451
Radioactive W aste Disposal
in Ocean (U. S. D ep't of
Commerce), 452
Symposium o n F a t i g u e
(Floyd and W dford, eds.),

88
B A l : See Dunercaprol
Symposium on Homan F ac­
Benzene hexachlorido: poison­
tors in Equipment Design
in g from, 457
(Floyd and W elford, eds,),
Benzidines; urinary output
270
•sr tf
284 544
estimation, 420
Toxicologic ties prodults
industrial toxicology, 79,157,
Beryllium
phytophamtaceutiqUM
258. 3S0, 440.,535
intratracheal imection of
(Fabre and T rubant), 451
legal medicine, 181, 36$, 538
Be* In rat, 375
Verhandiungen dcr deut­
mtdicitK and surgery, 263.
pneumoconiosis from, 164
schen Geseliechan fu r A rSSi, 44$
,
poisoning, 273
beitssdnita:
Band
11
occupational diseases and
Blood:
red
cell
cholinesterase
hazards, 13, 174, 253, 349,
Staube, Gase, DSmpfe
activity,
332
(Stidnkopff), 359
436, 5 »
.;
_
_ .
,
physiology and nutrition, 72, B o o x s
W orking Fitness of Older
A ir Pollution: Bibliography
173,435
M en (C lark), 451
(Davenport and Morgis), Books: Council on Industrial
■ radioactive substances and
x-ray, 181, 268, 356. 449,
H ealth list, 343
539
.
A ir Pollution and Com­ Brass-foundry operations: lead
ventilating, air conditioning,
munity H ealth (M ills),
intoxication from, 107
and engineering control,
270
Byssinosis,
164
85, 181, 267, 538
•
Compressed A ir Illness:
Accidents
Investigation During Con­
meefieri aspects, 453
struction of Tyne Tunnel,
syndrome, 66
1948-50 (Patou and W il­
Calcium ethylencdiamine-tetrader), 87
Aerosols: synergistic effects,
acetate; See Edathatnil
297
Flow and F a n : Principles
calcium
Air pollution
of Moving A ir Through
Cancer: See Carcinogens
la American cities, 28(1
Ducts (B erry), 271
committee report, 513
Histopathology of 5km, Ed. Carcinogens
diesel-engine exhausts, 113
Detroti-Wmdsor etudy, pre­
2 (Lever), 272
selection of chemicals for
test of forms »nd techIndustrial Dust, Ed, 2
carcinogenic s c r e e n in g ,
nwtuei, 47
(D rinker ra d H atch), 540
494
health b a w d s from, 397
Industrial V e n t i l a t i o n :
C ataract: radiation, 305
Air sampling
Manual of Recommended
of dost, 212
Practice, Ed. 3 (American Chemicals
physically toxic, 315
Conference of Govern­
physics of particle-size anal­
threshold lim it values for
mental Industrial Hygienysis, 431
1955, 521
Of smaii particulates, 422
tots), 360
Cholinesterase: ted cell ac­
Amyt nitrate: toxicity of
Lehrbuch dcr A rb e itsfa -'
tivity in whole blood, 332
vapor, 290
idene: Band II . SperieUe
Amhraeosie, 166, 168
Bcntfchygicno (Koelsch), Chromium compounds
dermatitis from chrome glue,
358
Antimony trfpxMe: toxicologic
368
. study, 473, 479
Modern Occupational Medi­
dermatologic a s p e c ts o f
Asfwstosis
cine (Fleming and others,
Chromate problem, 361
tGffcremiatcd from other
eds.), 359
e d a th a m ii c a lc iu m f o r
pneumoconioses, 208
Non tuberculous Diseases of
chrome ulcers, 123
"mehenat a b n o r m a litie s
Chest (Banyai, td.), 452 Coat mining pneumoconiosis
, from, 196
classification of roentgeno­
Occupational H ealth and
ll^ ' a t and mill workers,
Safety legislation (U . S.
gram s in, 17
Public H ealth Sendee),
epidemiological studies In
Wbology, 185
452
Great Britain, 2$

; 5

INDUSTRIAI H
D

Dbath :

Thompson, Lewie

Rycrs, 25 i
.
Decaborane 4
acute toxicity studies, 132
effect of repeated doses, 138
D erm atitis; "See also under
Chromium compounds
c o n ta c t, u n d e r O n ta r io
W orkmen’s Compensation
Act, 372
Diesel engines
amyl nitrate in fuel, toxicity
of, 290
aromatic hydrocarbons In
exhausts, 113
D im ercaprol: fo r mercury
poisoning, 231
D iptcrex: toxicity and mecha­
nism, 53
Ditertiarybutyhncthylphenol:
toxicity of, 93
D u st; air-borne, sampling of,

212 ■

insecticide*—Continued
Systox, 324
toxicity of Hexachlorocydopentadienc, 459
Iron rolling m ills: radiation
cataract in, 305
L
Lead
fume, filter papers for samp­
ling of, 243
intoxication in brass-foundry
operations, 107
urinary, effect of edathamil
calcium and dimercaprol,
231
L ungs: See also Asbcstosis;
Pneumoconiosis; Silicosis
occupational diseases, 183;
functional abnormalities in
fibrosto of, 196
partitional respirometry, 142
thorium effeet, 234

M
E
_
Fdatharnfl calcium
M ercury poisoning; edathamil
for chrome ulcers of skin,
calcium and dimercaprol
123
for, 231
for mercury poisoning, 231
P
F ilter papers: for sampling
lead fume, 243
Fluorescent tubes: toxicity of
phosphors, 473, 479
Fluoride
atmospheric, ion exchange
resins m determination of,
61
metaboiism, _ urinary excre­
tion by rabbit after renal
tube injury, 2
Food processing: toxicity of ditertiarybutylmethylphenol,
93

N
N bws a h p C omment , 101.
120, 217,289,296, 450, 472
Nitromethanc : toxicity of, 102
O
Occupational health programs,
393

Organophospborus compounds,
P

Tanning industry; ■chrott
ulcers, edathamil calciu
for, 123
•
Thorium refinery: indtutri
hygiene and medical $u
vey of, 234
,
Threshold limit values f<
19SS, 521
Toxicity, plysical, of
icals, 315

Parathion
drifting dust hazard, 403
spray concentrations and
U
residues, 408
Handicapped: employment
United States Q vil S
U.
S. government, 450 Particle-size analysis, 431
Particulates, air-bom «: samp­
employment of physl
Hescachlorocyclopentadiene
lin g technique; 422
handicapped, 450
toxicity of, 459
Periodicals:
Council
on
Indus­
United States N avy: physi
H ydrazine; subacute toxic
trial H ealth list, 343
fitness of executives
413
Petroleum
Industry:
health
of
shipyard, 121
Hydrocarbons,: aromatic,
w
orker,
126
United States Public Hep
diesel-engine exhausts,
Phosphors, calcium halophos­
Service: o c c u p a tio n a
phate: toxicologic study,
health program, 393
1
_ 473, 479
.
U ranium : particle
♦mein it n a/ TTeOe flllfiti
Industrial H ealth, Council on: P h o s p h o r u s ; t o x i c i t y o f
selected publications list.
organophosphorus c o m ­
343
pounds, 487
.
V
Insecticides
'
Pneumoconiosis: Sec also Asbestosis; Silicosis
benzene hexachloride poison­
Vanadium : bronchitis from,
ing, 457
classification of roentgeno­
505
■
gram s in, 17
dipterex, toxicity and mecha­
nism, 53
coal miners’, epidemiological
W
studies in Great Britain,
parathion: ' drifting dust
W
o
r
k
m
e
n
’s
compensation:
2
»
hazard,, 403; spray con­
contact dermatitis under
differential diagnosis, 208
centrations and residues,
O ntario act, 3?2
scientific exhibit, 159
408

6

SUBJECT

INDEX

TO

VOLUME 12

T he following Index contain« an alphabetical list of significant subjects presented in this
volume. Abstracts are indexed by category under the heading "A bstracts." Books reviewed arc
listed alphabetically by title under the heading “B ooks." Obituaries and death notices are
Indexed under the heading “D eaths .”
Occupational health news compiled by the United States H ealth Service is indexed separately
under the heading “ O c c u p a t io n a l H e a l t h N e w s ."
A
A b rin ; lethal Jewelry, 468
Absenteeism: sickness, 592

Ammonia: in air, deternuna-.
tlon of, 511
Asbestos t pulmonary disability
In workers, 198

A b str a c ts

B
accidents and their preven­
tion ; protective equipment,
Barium sulfate i radioactive
456, 562, 671
dust, pulmonary effects,
determination of air-borne
268
contaminants, 454,559,665
environmental
conditions, B attery w orkers: edaftamil
calcium-disodium for lead
453, 558
poisoning in, 528
general, 543
Bauxite
industry: health surindustrial toxicology, 450,
vcy
in British Guiana
5 5 2 ,6 »
community, 539
legal medicine. 671
medicine and surgery, 4S1, Beryllium
557
beryllium dust, 675
occupational diseases and
disability from, 174
hazards, 545, 657
radioactive substances and Blood vessels: pathology in
chest diseases, 7
x-ray, 456, 672
ventilating, a ir conditioning, B o o k s
and engineering control,
A irborne Contagion and A ir
455, 561,667
Hygiene (W ells), 564
A ir pollution (editorial), 583
D ust Is Dangerous (D a­
vies), Z27
in Florida, 567
Public H ealth Service com­
munity program, 462
A ir sampling: photomicrogra­
phy of air-hom e particles,
584
Aluminum
demonstration in animal tis­
sues, 218
in silicosis control: in cer­
amic« industry, 247; ex­
perimental, 229; in foun­
dry, 221; in gold nñntog»
250

Electroplating Engineering
Handbook (Graham and
Pinkerton, ids.), 365>
Factors Affecting Goats of
Hospital G u o (Hayes,
ed.), 566

B ooks—Continued
Hatogcnated Hydrocarbons;
Toxicity and Potential
Dangers (von Oettingcn),
369
Handbook of Emergency
Toxicology (Kaye), 566
Handbook of Medical Treat­
ment; Ed, 4 (Chatton and
others, eds,), 459
Human Element in Indus­
trial Accident Prevention
(Larson and others), 370
Legal Medicine, Pathology
and Toxicology, Ed. 2
(Gonzalez and o th ers),227
I-chrboch der Arbeitshygiane: Band I. AUgemeine
Physiologic und Hygiene
dcr A rbeit, Ed. 3 (Koclsch), 108
Mortality and Morbidity
D uring London Fog of
December, 1952; 564
Fncumokoniosen
(W orth
and Schiller), 45?
Skin (A llen), 458
Staubhingenerkrankungeo:
Band I I (J&tten and
others, eds.), 227
Textbook of Healthful Liv­
ing, Ed. 5 (Diehl), 458
W orkmen’s
Compensation
(Somers and Somers), 227

Financing H ospital Caro in
C
the United S tates: VoL XL.
Prepayment and the Com- Calcium silicate dust, hydrous:
effect on animat tissues,
munlty; VoL IIL F o r
348
Nonwage and Low-In­
come Groups (Becker, Carbon monoxide from pas­
senger ear engines, 678
ed.), 228

SUBJECT INDEX TO VOLUME 12
Carbon tetrachloride i
disease from, $22
Ceramics industry:
control ui) 247

Hver

silicosis

Chest diseases:
See also
l o n g s ; diseases by name;

Employee problems, 592
Employee sickness and health
sendees, costs, 472
•

I
Fluorine compounds: Indus*
trial uses and cutaneous
reaction, 412

ids
ire
are

M cIntyre-Saranac confer­
ence on, 1: papers read at,
1 ff , 109 ff„ 22? ff.

di

•Chlorine trifluoride: inhalation
toxicology, 515

F o g : photomicrography
particles, 584

Cholinesterase: activity levels
in normal subjects, 406

Foundry w orkers:
control in, 221

Chromium: reaction of com­
pounds w ith body tissues,
258

o s:
tfed

m).

Coal m ining: pulmonary dis• ability from, 204

ocy
6
eat-

an d

■

Xustion
370

Compensation, disability
for pneumoconiosis, 159
Wisconsin Act, physicians
and, 427

logy

s

Cobalt
’'
effect on animal lungs, 116
oxide, biological action, 124
particulate metal, biological
action, 127

)

Correction, editorial: estima­
tion o f loss of visual effici­
ency, 527

fcaM
dene
:» > -

D
idity
t of

Deafness, occupational, 643
,

D eaths : Peterson, Carl M ,
371

'orth

mi:
and

U v-

58
mtioa
>,227

j
I

1
m s:
•sues.

4
I

pas«78

H ydrocortisone: w ith neo­
mycin, for term inal pha­
langeal contusions, 388

Fluoroscopes,
for, 573

time

totalizer

India:
pneumoconiosis
K olar Gold Field, 73

Iro n ; ductile, odor problem,
571

of

silicosis

in

L
Labeling program of Manu­
facturing Chemists' Asso­
ciation, 378
Lead

Glass wool
biological action, 280
effects on animal lungs, 276
Gold mining
chest diseases in South
Africa miners, 33
pneumoconiosis in K olar
Gold Field, 73
.
pulmonary disability legisla*
tion in South Africa, 147
silicosis control in, 250
Great Britain
dust diseases in, 83
silicosis in, 86
Guiana, British: health survey
in mining community, 539
Gypsum
calcined dust, biological ef­
fects, 329
dust effects on lungs, 209

D u st: See also substances in­
volved
air-borne, particle count.
weight, shape, and rise, Hands
terminal phalanx contusions,
361
hydrocortisone-neom ycin
control in metal mines, 167
for, 388
differential susceptibility oí
cleaners, waterless, 572
animals to , 288
H
ealth
examinations; periodic,
diseases In G reat Britain, 83
420
ridioactiTe, clearance from
lung, 99
Hydrazine
in air, determination of, 511
E
in blood, “p y rid y r te st for,
Earths, rare i See R are earths
393
Edathamil cakmm-disodium:
methylated derivatives, tox­
for lead poisoning, $28
icity of vapors, 609

absorption, urinary porphy­
rins in, 396
poisoning, caldura-dlsodhim
for, 528
Legislation; pulmonary dis­
' ability, of South Africa,
147
Liver disease: from industrial
poisoning. 522
L ungs: See also diseases a f­
fecting, by n am e, sub­
stances injurious to, hy
name
’
biopsy, value of. 26
blood vessels in disease of, 7
clearance of radioactive dust
from , 99
disability
legislation
of
South Africa, 147
effects of rare metals, 116
M
M cIntyre Research Founda­
tion,. 2
M clntyre-Saranae Conference
on Occupational Chest
Diseases, 1
papers read at, X f f , 109 ff„
229 ff.
M anufacturing Chemists' As­
sociation labeling p ro ­
gram , 378
Metals
raining, dust control in, 167
rare, effects on anim al lungs,
116

7

A. M. A. ARCHIVES OF INDUSTRIAL HEALTH
Mines and mining

O c c u p a t io n a l H e a l t h N e w s

Postgraduate education,

226,

coal mines: See Coal mining

—Continued

dust control in metal mines,
■ 167

Occupational H ealth P ro ­
gram, advisory committee,
682

Potassium : antagonistic action
of $ÍO», 109

Pacific Northwest Industrial
H ealth Conference, 688

'‘PyrldyP’ test, for blood hy­
drazine, 393

Guiana mining community,
539
radon problem in deep-level
mining, 163

phosphoric ad d (hot) poi­
soning, 582

Q

vanadium, 63S

platinum electrode, rotating,
581

N

radiation survey meter re­
sponse, $80

gold mines: Sec Gold min­
ing

health survey in British

Naphthenic acid s: and their
metal salts, toxicity of,

477
Neomycin: w ith hydrocorti­
sone, for term inal phalanseal contusions, 389
N ew s and C omment , 107,
226, 368,461, 642
'
N-Nitrosodimethylamine: tox­
icology of vapor, 617
Noisc< environmental, 569
O
OCCUPATIONAL

HEALTH

News, 461. 567, 673
abrin, lethal jewelry, 468
a ir pollution: in Florida,
567} Public Health Serv­
ice community program ,
462
beryllium dust, 675

476

plastics industry,
problems, 470

hygiene

research grants in occupa­
tional health,- 576
solvents, 683; concentration
from spray-painting. 569
standard for places of em­
ployment, 568
telling the story, 575
threshold limit values, 685
uranium mining, 7-state con­
ference, 465
vanadium d u st 675

I

SVBÌEC

*•
'

S llicosisin Gres

i
'

pulmón
tlon i
Society n
Seal j
Solvents,

Quartz
antagonistic action of K*CO»,
109
dost, surface properties: bio­
chemical, 262; cytobiologkal, 266

compos
623
concent
palm
general
posit
509
Sonth Ai

R
Radiation
from barium sulfate dust,
628
clearance of radioactive dust
from hmg, 99
estimating Curie content of
p a c k a g e d r a d i o a c ti v e
wastes, 383
radon: See Radon
survey m eter response, 580

Oxalic a d d : industrial uses
and cutaneous reaction, Radium-dial industry: external
radiation exposure In, 503
412
. Radon
acute toxicity of, 435
Parndichlorobenzene :
liver
problem of, in deep-level
disease from, 522
mining, 163
Petroleum industry: toxicity
of naphthenic ad d s and R are earths
their metal salts, 477
biological action, 301, 306
Phusphoric a d d (hot) : poi­
effects on animal lungs, 297
soning, 582
S
Photomicrography: of air­
P

carbon monoxide from pas­
senger car engines, 678
dusts, organic, beryllium,
and vanadium, 67$
borne particles, 584
Saranac Laboratory, 4
employee sickness and health
Plastics industry, hygiene prob­ Silicosis
’
services, cost«, 472
lems, 470
aluminum
prophylaxis
and
fluoroscopes, time totalizer
therapy in ceramics Indus­
Platinum electrode, rotating,
for, 573
try , 247; experimental,
581
hand ekaners, waterless, 572
229; in foundry, 221; in
Pneumoconiosis
industry health plan, 567
gold mining, 250
compensation, evaluation of,
iron, duetije, odor problem,
antagonistic action of SiCh
159
571
and K & O * 109
. .
dust
diseases in Great
micropipette control, home­
in Canada, 56, 63
Britain, 83
made, 688
control, in gold mining, 250
in
K olar Gold Field, 73
noise, environmental, $69
epidemiologic Study in U . S.,
talc, 66
nursing fellowships, 687
48
occupational health "detec­ Porphyrinst urinary, jq lead
in gold miners o f South
absorption, 396
Africa, 33
tiv e " 673

ehest d
in,

pnlmor
tian,

Talc
dust,e
317

TH

SUBJECT INDEX TO VOLUME 12
►
Talc—Continued

Silicons—Continued
226,

j

in G reat B ritain, 86
pulmonary disability legisla­
tion in South Africa, 147
Society n ew s; American Med­
ical Association, 642
Solvents, 683
composite, toxicity of vapor,
623
concentration from
painting, 569

Mo­

generating vapor with com­
position of parent solvent,

509
South Africa, Union of

itili,

it of
tire
580
T ra i
.503

306
,2 9 7

an d
« in s .

total,
t ; fa
S iO .

; 250

xs.

90Qtn

li' )

Tantalum oxide
biological action, 121
effect on animal lungs, 116

Tungsten
carbide and carbon; bio­
logical action, 137; effects
on animal lungs, 116

chest diseases in gold miners
fa, 33

carbide and cobalt; bio­
logical action, 140; effects
on animal lungs, 116

pulmonary disability legisla­
tion, 147

effects on animal lungs, 116

th a t

T...
T alc
dust, effects on animal tissue,
317

Uranium Mining—Continued
radon problem, 163
radon toxicity, 435

pneumoconiosis, 66

ThiopKospbitca:
toxicologic
studies on trim ethyl- and
triethyltritiuophosphites,
spray­
483

:o*
tto .

mining dust inhalation ef­
fects, 182

particulate metal, biological
action, 134
U
Uranium mining
on Colorado Plateau, 375

V
Vanadium dust, 675
Vanadium ore : health
workers with, 635

of

Vanadium toxicology; finger­
nail cystine fa, 494
V apor toxicity; See also sub­
stances involved
of composite solvent, 623
generating vapor w ith com­
position of parent solvent,
509
V ision; estimation of loss of
visual efficiency, 439, 527
W
W isconsin W orkm en's Com­
pensation A c t; physicians
and, 427

OCCUPATIONAL CANCER HAZARDS IN
AMERICAN INDUSTRIES
W. C. HUEPER, M.D.
BETHESDA, MD.

M

OD ERN industry has brought along a considerable number and variety of
carcinogenic agents and, no doubt, will bring ever new ones as it develops
new methods of production and new products and applies established methods and
agents to new purposes. If we look at the long and ever-growing list of known
and suspected occupational carcinogenic agents, if we contemplate their widespread
existence as industrial wastes contaminating air,*1 water, and soil of the wastedisposal areas of industries, if we consider their presence in many products of daily
consumption, we have the general spectrum of the cancer hazards which originate
from our modern industrial development. Control measures must be based on the
realization of this wide potential scope of carcinogenic contacts. They must con­
cern not only workers engaged in the production or the use of carcinogenic agents
but also the population living in the environment of plants with carcinogenic
hazards, as well as the general public.2 It is well to remember that experience with
occupational cancer has demonstrated that, given a carcinogenic agent and proper
conditions of exposure, the occurrence of cancer among the exposed individuals is
merely a question of time. The incidence rate and the length of the latent period
depend mainly on the relative potency of the carcinogenic agent present and the
intensity of the exposure. The lack of adequate epidemiologic studies and the
usually long latent period of exogenous cancer often obscure the appreciation of
causal relations between occupational factors and cancer.
.
A few illustrations as to the distribution of exogenous carcinogenic hazards of
industrial origin may be appropriate. For instance, men engaged in the mining and
smelting of copper, zinc, and silver ores are exposed to arsenicals. The makers and
users of arsenical pesticides that are employed in the form of sprays or dusts suffer a
similar exposure, as do patients who receive arsenical medication. Beyond these
rather narrow circles of producers and consumers of arsenicals stands that appre­
ciable part of the general population that comes in direct or indirect contact with
arsenicals released into the atmosphere with smelter flue dusts or as a result of
From the National Cancer Institute.
Address presented at a meeting of the Cancer Prevention Committee in New York on
June IS, 1949.
.
Dr. Hueper is Chief, Cancerigenic Studies Section, Cancer Control Branch, National Insti­
tutes of Health, Public Health Service, Federal Security Agency.
1. Hartwell, J. L.: Survey of Compounds Which Have Been Tested for Carcinogenic
Activity, U. S. Public Health Service, 1941. (371 pp.)
2.
Hueper, W. C.: Environmental and Occupational Cancer, U. S. Public- Health Reports
1948, Supplement 209. (68 pp.).
.
.
204

HUEPER—OCCUPATIONAL CANCER HAZARDS

205

large-scale dusting of orchards and cotton fields or from the use of sprays in truck
gardens. Arsenicals may enter the human body in drinking water that passed as
rain water through arsenic-containing slag heaps of smelters. The consumption
of fruits, fruit juices, and wines contaminated with arsenical insecticides affords
another source.
In the field of organic chemistry we meet with bladder cancers among pro­
ducers and handlers of certain aromatic amines, and find that some of these amines
are used in the manufacture of pharmaceuticals and that their derivatives are
employed as flotation agents in the mining industry and as antioxidants in the
manufacture of rubber. Finally, dust and fumes from aromatic-amine operations
that have been improperly conducted as to exhaust ventilation may endanger not
only workers in adjacent operations but also thé population living in the fume zone
of the plant. A similar environmental contact with vaporized aromatic amines may
result from the burning of emptied containers on open lots within populated areas.
Carcinogenic soot or tar fumes cause cancer of the lungs and skin not only in
stokers of coke ovens but also in makers of products for which heated tar and
asphalt are used, for example tar paper and asphalt shingles. The possibility must
be considered that carcinogenic hydrocarbons of industrial origin may cover as a
film the extremely small particles of flue dust and exhausts of petroleum-cracking
units. The question has been raised whether a similar hazard exists in concrete
factories in which soot-producing diesel engines are used. Carcinogenic soot may
also be released into the atmosphere during the manufacture and industrial use of
carbon black obtained from oil residues or natural gas or from the burning of waste
oils near refineries, causing an occupational and environmental hazard. Carcino­
genic oil and tar dusts from oiled or tarred roads present a potential hazard, involv­
ing the general population. Similar considerations apply to other carcinogens,
such as metallic and radioactive ores.
The recognition of carcinogenic agents and exposures is a prerequisite to a
rational and intelligent occupational cancer control. Epidemiologic surveys of plant
populations are very important in this respect. Exogenous occupational carcinogens
not only excessively increase the cancer incidence rate of one particular organ but
may elevate the total cancer incidence rate and primary cancer multiplicity. Like­
wise, not only workers exposed to aromatic amines show a high liability to bladder
«uicer, but also workers in gas plants. Thus, specific cancer sites are not neces­
sarily indicative of any particular type of carcinogenic agent. Several agents may
exert synergistic action when acting simultaneously or successively, or may
independently produce cancer at a certain site.
It may be worth while mentioning here that leukemia may result from lowlevel, prolonged, and diffuse exposure to x-rays, radioactive agents, or benzol.
Nasal sinus cancers have been observed in men exposed to a volatile nickel com­
pound (nickel carbonyl) in the course of nickel refining. Lung cancers have been
observed in chromate workers. The use of metals in abrasives and as catalysts in
the organic chemical and the petroleum industries as well as the production of metal
dusts and mists or vapors in welding, spraying, and polishing operations and in the
production of alloys from metal powders may greatly extend the potential scope of
occupational metal cancers and may introduce occupational cancer hazards where
these are not readily suspected.

206

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE

One of the most important attributes of many exogenous carcinogens is their
ambivalent properties; i. e., depending on the intensity of action or the dose, they
may produce manifestations either in the degenerative, necrotizing, aplasiogenic
range or in the hyperplastic, canceroid, leukemoid, cancerous range. In studying
a worker population for the presence of a carcinogenic agent, a wide range of
abnormal symptoms may be noted representing a diagnostically significant syn­
drome which I have termed the environmental-carcinogen pattern. Thus, an
individual who develops an occupational carcinoma may exhibit not only various
types, of proliferative, precancerous reactions but, preceding or accompanying these
hyperplastic reactions, manifestations which are of the degenerative, atrophic,
' necrotizing type. Likewise, various members of a worker population exposed to
the same carcinogenic agent at different dose levels may display abnormal reactions
representing the entire scale of the environmental-carcinogen pattern. Thus, in a
benzol operation some workers may suffer from aplastic anemia, others from
moderate anemia and leucopenia, a third group may display hyperleucocytosis and
polycythemia, while still others may have leukemoid and leukemic reactions. A
similar hematic syndrome may be seen in persons exposed to x-rays. Whenever
a plant physician observes even parts of such environmental-cancer patterns, he
should become alerted to the possibility of a carcinogenic hazard in the operation
in which the affected workers are employed.
Other important clues in this respect may be obtained from the demonstration
of excessive incidence of cancer in special groups of workers and also from shifts
of the sex ratio of cancer incidence. For instance, the male-female ratio of lung
cancer incidence is approximately 5:1. Merewether recently reported 31 cancers
of the lung associated with asbestosis in a series of 235 cases of asbestosis. There
was not only an excessive lung cancer incidence in this group (13.2%), but the
male-to-female sex ratio of the cancer cases stood at 2:1.
The histologic type of cancer is as a rule of no significance as a clue concerning
an occupational or a nonoccupational origin. However, in the case of lung cancers
it appears as if an increasing preponderance of squamous cell and anaplastic
cancers over adenocarcinomas favors an occupational or exogenous origin or per­
haps more exactly reflects the action of a respiratory carcinogen. Thus, shifts in
the ratio of squamous cell cancers to adenocarcinomas of the lung may have an
etiologic significance and may indicate not only that an occupational carcinogen
is present in a particular operation but that the injurious agent occurs in the form
of a gas, vapor, mist, dust, or fume. It is not likely, on the other hand, that the
inhalation of dust or mists might elicit cancers in the nasal sinuses, because the
narrow passages leading to these cavities would prevent matter of relatively large
particle size penetrating into these cavities. However, gases, vapors, fumes, and
colloidal dust of carcinogenic property might enter the nasal sinuses.
It is obvious not only that the various types of information mentioned are
essential for the discovery of an occupational cancer hazard and for the identifi­
cation of the causative agent but that they are of utmost importance for the
. subsequent development of effective preventive and precautionary measures. The
acquisition of these data thus forms a part of any sound control program and in
fact represents the foundation of it.

HUEPER—OCCUPATIONAL CANCER HAZARDS

207

. While it is not possible to discuss here the full scale of control measures that
might or should be applied in the numerous and different carcinogenic operations,
■it may be advantageous to present general directives and a few specially important
considerations.
Since we do not know the minimal effective dose of any of the many occupa­
tional carcinogens, it seems obvious that they should be completely eliminated
wherever that is practical. This can be done by using or producing suitable non­
carcinogenic substitutes; ft is usually feasible without creating serious production
difficulties to replace benzol by other organic solvents having similar effectiveness.
In the case of the highly hazardous beta-naphthylamine it is possible to eliminate
the hazard by starting with a sulfonated beta-naphthol which is later aminated and
. which in a sulfonated form is not carcinogenic. A closed system of production in
which all hazardous phases are carried out is another effective method of elimi­
nating cancer hazards in industry. Wherever bulky material is handled, the adoption
of a closed system of production may be difficult. Then other means must be found
to eliminate or considerably reduce the carcinogenic hazard. The goal may some­
times be obtained by changing from a dry method having a dust hazard to a wet
method. Good housekeeping in plants and personal hygiene of the workers are
other ways to reduce hazards. Good exhaust ventilation is essential wherever dust,
fume, vapor, mist, or gas hazards exist. However, care should be taken that the
carcinogenic material is removed from the exhaust air before the wastes are
released into the atmosphere and that none of such wastes are blown into adjacent
working places and living quarters. Many of the more recently constructed indus­
trial plants are built in such a way that the machinery stands either free or in an
open-air shelter, so that any injurious gases, fumes, or vapors may be readily
dispersed into the surrounding atmosph&re and thereby become harmless through
dilution.
While such a system may be suitable for some carcinogenic hazards, it seems
to be unsuitable for others, especially for those which are due to agents that are
not readily decomposed but accumulate on the ground and in the water and thus
may gradually reach dangerous concentrations.
In instances in which the carcinogenic factor represents only a very small
portion of the entire product, as in tar, pitch, petroleum derivatives, and similar
products, an attempt should be made to develop either production methods through
which the production of carcinogenic contaminants is avoided, or, when this is not
possible, to remove or destroy the carcinogenic portion in the hazardous product.
Until such measures have been developed other procedures are being utilized. In
the case of carcinogenic oils or tars, these procedures consist in diluting the oil or
tar with noncarcinogenic material so that the carcinogenic potency is lost or reduced
to such a.low degree that any potential cancer resulting from prolonged and repeated
contact with such products has a latent period surpassing the average life span
of man.
While such engineering and technical measures are of utmost importance in
the control of occupational cancer, the intelligent and ready cooperation of the
workers in observing additional precautionary measures when handling cardnogenic material should be obtained. Unless the handlers are informed of the hazards
connected with their work, they cannot be expected to follow rules and regulations
' issued by management. Only when they know and realize the potential risks which

208

INDUSTRIAL HYGIENE AND OCCUPATIONAL MEDICINE

carelessness may entail, can they be expected to cooperate intelligently. It seems
only fair to industrial users and the general public that a reasonable amount of
information about the existence and types of occupational carcinogens is made
available to them, so that such hazards cannot be spread or sustained any longer
by sheer ignorance of such matters. This does not imply that such information
has to make headlines in newspapers, but in a quiet way, preferably, through trade
circles, pertinent data on recognized, suspected, and potential carcinogenic agents
should be distributed, so that the necessary technical and commercial adjustment
processes can be initiated and carried out in an orderly fashion without causing
any serious disruptions in the industrial, economic, and social pattern.
Without any doubt, a great deal of educational work has to be done in medical
circles so that the members of the medical profession become aware of the existence
of occupational cancer hazards and learn to discover and evaluate properly pre­
cancerous conditions and thereby aid industrial management in controlling occu­
pational canceration effectively from a medical standpoint. While medical efforts
are not likely to reduce in any fundamental fashion existing cancerigenic conditions
in industrial plants, they can contribute definitely in alleviating the prognosis of
the unfortunate victims.
While much evidently remains to be done in controlling occupational cancer
hazards, I do not believe that mankind will succeed in eliminating them completely.
As little as this result was obtained in connection with contagious diseases, all of
which to some degree are still with us, so will our best efforts fail of entirely
eradicating occupational cancers. These will remain with us as manifestations of
our self-created modern industrial environment from which we are unable to escape
and which we can modify only within certain limits. Though cancer is one of the
risks of living, we doubtless shall succeed in reducing these risks to a considerable
• degree, particularly where they are excessive, for occupational-industrial reasons.
'

(The two works referred to in Footnotes 1 and 2 are available at a cost of $1 and of
20 cents, respectively, -from the Superintendent of Documents, U. S. Government Printing
Office, Washington 25, D. C.)

ABSTRACT OF DISCUSSION
The question was raised as to the feasibility of avoiding the betanaphthylamine hazard by
sulfonatioa Dr. Hueper stated that the use of sulfonated beta-naphthol as a starting material
is a process developed in Switzerland.* It has not as yet been employed in the United States.
Pr. Hueper also stated that he had noted the use of alpha-naphthylamine in the preparation of
pharmaceuticals. He pointed out that commercial alpha-naphthylamine always contains some
beta-naphthylamine, which apparently has been responsible for the occurrence of bladder cancer
among alpha-naphthylamine producers.
Radioactive materials were considered with reference to the need of long-range planning
. for disposal of radioactive wastes.
The problem of latency was discussed. Dr. Hueper stated that the latent period of tumors
induced by the following materials increases in the order shown: tar, pitch, shale oil, petroleum.
It was the consensus that the employment of elderly rather than young persons should be
recommended for tasks involving uncontrolled carcinogenic hazards. The view was that the
life span of elderly workers would run out before cancer could be induced by the materials to
which they were exposed,
3.
Muller, A.: Ueber Blasen- und Nierenschadigungen in der Farbstoffindustrie, Helvet.
chir. acta 18:1-41, 1951.
.
f

)