ST 0853668 PLAINTIFF’S EXHIBIT DOW-2051 Society of Toxicology History 1961-1986 by Harry W. Hays, Ph.D. Historian assisted by Florence M. Carieton, M.S. ST0853669 DR. VON OETTINGEN It is often difficult to determine to what extent a man has influenced the course of events through scientific research, but there is no doubt that Dr. Wolfgang Felix von Oettingen, known to many as Dr. Von, has made an outstanding contribution to both experimental and clinical toxicology. Dr. von Oettingen was bom in Marburg, Germany, on December third, 1888. He received his Ph.D. degree in chemistry from the University of Got­ tingen in 1913 and his degree in medicine from the University of Heidelberg in 1916. It was at Gottingen that he developed his first interest in toxicology as a result of his studies on the chemistry of reduced santonin. The inspira­ tion he had received from such men as Krehl, Gottlieb, and Wallach led him to seek greater opportunities for research than were available in post-war Germany and in 1924, Dr. Von decided to come to America. His first post was at the University of Illinois and not long after his arrival there, he was invited by Dr. Torald Sollmann to join the Department of Pharmacology at Western Reserve University. Although his research work was largely devoted to problems in pharmacology, his interests turned more and more toward toxicology. In 1934, Dr. Von became the first Director of the Haskell Laboratories of Industrial Toxicology. By 1938, the opportunity to direct research on an even broader scale induced him to accept the post of Industrial Toxicologist at the National Institutes of Health. It was here that he served for nearly twenty years, publishing on a wide range of subjects, which included original investiga­ tions as well as extensive reviews. The prestige of Dr. von Oettingen as a toxicologist is recognized throughout the world but only those who have come to know him personally can appre­ ciate the bigness of his heart, the gentleness of his approach and the warmth of his personality. It is with great pleasure that the Society of Toxicology, at this, its first an­ nual meeting, awards this certificate of Honorary Membership to Dr. Wolfgang Felix von Oettingen. Presented by: Dr. Harry W. Hays April 15, 1962 16 ST 0853670 If adopted the officers would immediately file the articles of incorporation and at the next annual meeting a statement would be made that the old society no longer exists. It was moved and seconded that the resolution be adopted and was over­ whelmingly approved. Dr. Shaffer expressed his thanks to William Hays for helping the Society through this major step and to the members for their support during his term of office. ETHEL BROWNING, M.D. We owe great debts of gratitude to those individuals who have the ability, patience and understanding to chronicle events, collect and tabulate informa­ tion and facts so that the remainder of us less well endowed mortals will be the richer for their labours. Without their labours we should be adrift on the unchartered seas of jumbled facts and fallacies, and blown hither and thither in our searches for the truth. Amongst the chroniclers of the toxicity of materials and the effects of their toxicity, is pre-eminently Dr. Ethel Browning. Dr. Browning’s books are known to all of us. Their compilation has been a laborious task undertaken whilst acting in capacities of pathologist, industrial physician and hygienist. Her numerous writings cover many subjects with a clarity, precision and succinctness that are models of scientific exposition. Even now, though retired from her former position as H.M. Medical Inspec­ tor of Factories, Dr. Ethel Browning is occupied with numerous literary jobs including the editing of Elsevier Monographs on Toxic Agents and a new Encyclopaedia of Occupational Medicine. However, we honour Dr. Browning not only for her literary accomplish­ ments in toxicology but her steadfastness in promoting the health and welfare of workers with toxic materials. From general practice and the specialty of pathology, Dr. Browning moved into the sphere of industrial toxicology when the only light was the light of her microscope in the dark days and nights of the war years. How many industrial intoxications from lead, benzene and other solvents she prevented and how many iron deficiencies she corrected we shall never know. Above all, Dr. Browning is a lady, a source of help and advice on matters human and toxicological, sf gracious host and a lover of people. Fortunate it was indeed for industrial medicine and toxicology when injury itself led her into medicine. The Society of Toxicology awards with pleasure and satisfaction the Certi­ ficate of Honorary Membership to Ethel Browning, M.D. 24 ST085367I Appendix IV SOCIETY OF TOXICOLOGY, INC. 1961-1962 Arnold J. Lehman HONORARY PRESIDENT: PRESIDENT: Harold C. Hodge VICE PRESIDENT: Kenneth P. DuBois SECRETARY: Harry W. Hays TREASURER: William B. Deichmann COUNCIL: The Officers and Frederick Coulston, Victor A. Drill, Paul S. Larson and C. Boyd Shaffer SOCIETY OF TOXICOLOGY, INC. Membership List ADAMS, Edgar M., Ph.D. Asst. Dir., Biochemical Res. Lab. The Dow Chemical Company Midland, MI BECKER, Bernard A., M.S. Head, Research Pharmacology Section Strasenburgh Laboratories Rochester 3, NY AMBROSE, Anthony M., Ph.D. Assoc. Prof., Dept, of Pharmacology Medical of Virginia Richmond 19, VA BENITZ, Karl-Friedrich, M.D. Head, Dept, of Experimental Pathology Lederle Laboratories Pearl River, NY BACK, Kenneth C., Ph.D. 460 Ketcham Street Dayton 31, OH BEYER, Karl H., Jr., M.D., Ph.D. Vice President Merck Sharp St. Dohme Research Labs. West Point, PA BAGDON, Robert E., Ph.D. Senior Toxicologist Hoffimann-La Roche Inc. Nutley, NJ BLOOD, Frank R., Ph.D. Professor of Biochemistry Vanderbilt Univ. School of Medicine Nashville, TN BALAZS, Tibor, D.V.M. Food and Drug Directorate Dept, of National Health and Welfare Ottawa, Ontario, Canada 197 • I ST 0853672 BOOTH, Albert N., Ph.D. U.S. Dept. Agric. Western Util. Res. Div. 800 Buchanan Street Albany 10, CA CHENOWETH, Maynard B., M.D. Biochemical Research Laboratory The Dow Chemical Company Midland, Ml BOYD, Carl E., M.D. Food and Drug Laboratories Dept, of National Health and Welfare Ottawa, Ontario, Canada CHRISTENSEN, Herbert E., Major, USA Armed Forces Institute of Pathology Washington 25, DC BOYD, Eldon M., M.D. Head, Dept, of Pharmacology Queen’s University Kingston, Ontario, Canada CLEMENTS, Gerald R., Ph.D. Head, Dept, of Pathology and Toxicology Armour Pharmaceutical Company P.O. Box 511 Kankakee, IL BRAUN, Herbert A., Ph.D. Chief, Bioassay Sec., Pharmacology Div. Food and Drug Administration Washington 25, DC . COON, Julius M., M.D., Ph.D. Head, Dept, of Pharmacology The Jefferson Medical College Philadelphia 7, PA BRODY, Theodore M., Ph.D. Assoc. Prof., Dept, of Pharmacology University of Michigan Ann Arbor, MI CORNISH, Herbert H., Ph.D. Asst. Prof., Dept, of Industrial Health Univ. of Mich., School of Public Health Ann Arbor, MI CARPENTER, Charles P., Ph.D. Mellon Institute of Industrial Research 4400 Fifth Avenue Pittsburgh 13, PA COULSTON, Frederick, Ph.D. Dir., Exper. Pathology and Toxicology Sterling-Winthrop Research Institute Rensselaer, NY CASARETT, Louis J., Ph.D. Asst. Prof. Radiation Biol. &. Pharmacol. Univ. Rochester Atomic Energy Proj. Rochester 20, NY DAVIDOW, Bernard, Ph.D. Chief, Food &. Drug Lab., Dept. of Health 125 Worth Street New York 13, NY 198 i i ! 9 I I ST0853673 DAVIS, Kent J., D.V.M. Veterinary Pathologist Food and Drug Administration Washington 25, DC DRILL, Victor A., M.D., Ph.D. Director of Biological Research G.D. Searle &. Company Box 5110 Chicago 80, IL DEARBORN, Earl H., M.D., Ph.D. Asst. Dir., Exper. Therap. Res. Sec. Lederle Laboratories Pearl River, NY DROBECK, Hans P., Ph.D. Toxicology &. Exper. Path. Sec. Sterling-Winthrop Research Institute Rensselaer, NY DEICHMANN, William B., Ph.D. Chairman, Dept, of Pharmacology Univ. of Miami School of Medicine Coral Gables 34, FL DU BOIS, Kenneth P., Ph.D. Dir., USAF Radiation Laboratory 930 East 58th Street Chicago 37, IL DELAHUNT, Charles S., D.V.M. Manager of Toxicology Chas. Pfizer &. Co., Inc. Groton, CT DURBIN, Charles G., V.M.D. Veterinary Medical Director Food and Drug Administration Washington 25, DC DIERMEIER, Harold F., Ph.D. Senior Research Pharmacologist Lederle Laboratories Pearl River, NY DURHAM, William F., Ph.D. Chief, Wenatchee Field Station Communicable Disease Center, USPHS Box 73 Wenatchee, WA DOMINGUEZ, Abel M., Capt., USAF Toxicology Lab., Aerospace Path. Branch Armed Forces Institute of Pathology Washington 25, DC DOULL, John, M.D., Ph.D. Asst. Dir., USAF Radiation Lab. 927 E. 57th Street Chicago 37, IL. DOWNS, William L., M.S. Asst. Prof, of Radiation Biology Univ. Rochester School of Medicine Rochester 20, NY EAGLE, Edward, Ph.D. Head, Div. of Physiol., Toxicol. &. Histol. Swift * MUNCH, James C., Ph.D. Dept. Pharmacol., Hahnemann Med. Coll. 213 North 15th Street Philadelphia, PA MATSUMOTO, Hiromu, Ph.D. Biochemistry Department University of Wisconsin Madison 6, WI « MURPHY, Sheldon D., Ph.D. Div. of Air Pollution, USPHS 4676 Columbia Parkway Cincinnati 26, OH MAYNARD, Elliott A., Ph.D. Assoc. Prof, of Pharmacology Univ. Rochester School of Medicine Rochester 20, NY NAIR, John H., Ill, M.S. Tech. Dir., Syracuse Univ. Res. Corp. 1075 Comstock Avenue Syracuse 10, NY 204 t ST 0853679 NASH, Joe B., Ph.D. Assoc. Prof., Pharmacology Sc Toxicology University of Texas Medical Branch Galveston, TX PACKMAN, Elias W., D.Sc. Assoc. Dir., LaWall Sc Harrisson Res. Labs. 1921 Walnut Street Philadelphia, PA PALLOTTA, Arthur J., Ph.D. Director of Research Bionetics Research Labs., Inc. Box 26 Falls Church, VA NEWBERNE, James W., D.V.M. Asst. Head, Pathology Dept. Pitman-Moore Company Indianapolis, IN NEWELL, Gordon W., Ph.D. Asst. Dir., Life Sciences Division Stanford Research Institute Menlo Park, CA PALMES, Edward D., Ph.D. Inst, of Industrial Med., NYU Med. Center 550 First Avenue New York 16, NY OBERST, Fred W., Ph.D. Chief, Gassing Br., Toxicology Div. U.S. Army Chem. Res. Sc Development Labs. Army Chemical Center, MD PAYNTER, Orville E., Ph.D. Chief, Primate Laboratory Hazleton Laboratories Falls Church, VA PECK, Harold M., M.D. Dir. of Pathology and Toxicology Merck Sharp Sc Dohme Research Labs. West Point, PA OESTER, Yvo T., M.D., Ph.D. Stritch School of Med., Loyola Univ. 706 South Wolcott Avenue Chicago 12, IL PENALVER, Rafael A., M.D. Department of Medicine Univ. Miami School of Medicine Coral Gables 34, FL OPDYKE, Donald L.J., Ph.D. Head, Toxicology Research Program Procter Sc Gamble Miami Valley Labs. Cincinnati'39, OH PLAA, Gabriel L., Ph.D. Dept.,of Pharmacology, Coll, of Med. State University of Iowa Iowa City, lO OSER, Bernard L., Ph.D. Dir., Food Sc Drug Research Labs. Inc. Maurice Avenue at 58th Street Maspeth 78, New York, NY PLUMMER, Albert J., M.D., Ph.D. Director of Macrobiology Ciba Pharmaceutical Products Inc. Summit, NJ 205 ST0853S80 POZZANI, Urbano C., M.S. Mellon Institute 4400 Fifth Avenue Pittsburgh 13, PA SAUNDERS, Jack P., Ph.D. Division of Research Grants National Institutes of Health Bethesda 14, MD PROCTOR, Charles D., Ph.D. Stritch School of Med., Loyola Univ. 706 S. Wolcott Avenue Chicago 12, IL SCHOLLER, Jean, Ph.D. Sr. Pharmacologist, Toxicology Dept. Stanford Research Institute Menlo Park, CA PUNTE, Charles L., B.S. Chief, Aerosol Branch US Army Chem. Res. &. Development Labs. Army Chemical Center, MD SEIFTER, Joseph, M.D. Dir. Basic Medical Sciences Res. Wyeth Laboratories, Inc. Box 8299 Philadelphia 1, PA RADOMSKI, Jack L., Ph.D. Professor of Pharmacology Univ. Miami School of Medicine Coral Gables 34, FL SHAFFER, C. Boyd, Ph.D. Dir. Envir. Hlth., American Cyanamid Co. 30 Rockefeller Plaza New York 20, NY ROBINSON, Virgil B., Ph.D. Head, Pathology Dept., Research Labs. Pitman-Moore Company Box 1656, Indianapolis, IN SHERMAN, Martin, Ph.D. Professor of Entomology University of Hawaii Honolulu 14, HI ROSEN, Harry, Ph.D. Sr. Scientist - Pharmacology Wyeth Laboratories Inc. Philadelphia 1, PA SIEGEL, Jacob, Capt. USNR U.S. Navy Toxicology Unit National Naval Medical Center Bethesda 14, MD ROUDABUSH, Robert L., Ph.D. Laboratory of Industrial Medicine Eastman Kodak Company Rochester 15, NY * SMITH, Frank A., Ph.D. Assoc. Prof., Radiation Biology Univ. Rochester Atomic Energy Project Rochester 20, NY ROWE, Verald K., M.S. Biochemical Research Laboratory The Dow Chemical Company Midland, MI SMITH, R. Blackwell, Jr., Ph.D. Pres., Medical College of Virginia Box 606, MCV Station Richmond 19, VA 206 I I t i ■t t ST085368I SNYDER, Fred H., Ph.D. Procter &. Gamble Ivorydale Technical Center Cincinnati 17, OH ♦SOLLMANN, Torald H., M.D. 14327 Superior Road Cleveland 18, OH TAMAS, Anton A., M.D. Chief, Toxic Hazards Section Aerospace Med. Lab., ASD (ASBMPT) Wright-Patterson Air Force Base, OH TAYLOR, Jean M., Ph.D Head, Direct Food Additives Unit Food and Drug Administration Washington 25, DC SPERLING, Frederick, Ph.D. Dir. Sperling Labs. Div., Foster D. Snell 1500 Guilford Avenue Baltimore 2, MD STAVINOHA, William B., Ph.D. Federal Aviation Agency Civil Aeromedical Research Institute Box 1082, Oklahoma City, OK STERNER, James H., M.D. Med. Dir., Eastman Kodak Company 343 State Street Rochester 4, NY STOKINGER, Herbert E.. Ph.D. Chief Toxicologist, U.S.P.H.S. 1014 Broadway Cincinnati 2, OH SVIRBELY, Joseph L., Ph.D. R.A. Taft Sanitary Engineering Center 4676 Columbia Parkway Cincinnati 26, OH TH1ENES, Clinton H., Ph.D. Dir., Institute of Medical Research Huntington Memorial Hospital Pasadena, CA TISLOW, Richard F., M.D., D.Sc. Chief Pharmacologist Wyeth Institute for Medical Research Box 8299 Philadelphia 1, PA TREON, Joseph F., Ph.D. Mgr., Biological Sciences Section Atlas Chemical Industries, Inc. Wilmington 99, DE TUSJNG, Thomas W., M.D. Director of Research Hazleton Laboratories Inc. Box 30 Falls Church, VA « VAN ARMAN, Clarence G., Ph.D. Mgr., Pharmacological Evaluation Sec. Wyeth Laboratories Inc. Radnor, PA TAINTER, Maurice L„ M.D. Vice Pres., Sterling Drug Inc. 1450 Broadway New York 18, NY 207 ST0853682 VINSON, Leonard J. Lever Bros. Co. Research Center 45 River Road Edgewater, NJ WEIL, Carrol S., M.A. Mellon Institute 4400 Fifth Avenue Pittsburgh 13, PA ♦VON OETTINGEN, W.F., M.D., Ph.D. 5802 Wyngate Drive Bethesda 14, MD WEISBURGER, John H., Ph.D. Head, Carcinogen Screening Section National Cancer Institute, NIH Bethesda 14, MD WARD, John W., Ph.D. A.H. Robins Company, Inc. 1407 Cummings Drive Richmond, VA WEST, Bob, Ph.D. Asst. Dir., Rosner-Hixson Labs. 7737 S. Chicago Avenue Chicago 19, IL WAZETER, Francis X., Ph.D. Head, Chronic Toxicity Unit Merck Inst, for Therapeutic Research West Point, PA WHITE, Norman G., Ph.D. Mgr. Ind. Hyg. Dept., Shell Chemical Corp. 50 West 50th Street New York 20, NY WEAVER, Lawrence C., Ph.D. Head, Biomedical Res. Dept. Pitman-Moore Company Indianapolis 8, IN WILLIAMS, Martin W., Ph.D. Box 945 Benson, AZ WEBSTER, Stewart H., Ph.D. Lab. of Pharmacology &. Toxicology NIAMD, National Institutes of Health Bethesda 14, MD WOODARD, Geoffrey, Ph.D. Woodard Research Corporation P.O. Box 405 Herndon, VA WORDEN, Alastair N., M.A. Director of Research Nutritional Research Unit Huntingdon, England WEEKS, Maurice H., M.S. Gassing Branch, U.S. Army Chemical Research &. Development Labs. * Army Chemical Center, MD YONKMAN, Frederick F., M.D., Ph.D. Vice Pres, in charge of Research Ciba Pharmaceutical Company Summit, NJ WEIKEL, John H., Jr., Ph.D. Assistant Department Director Mead Johnson Research Center Evansville 21, IN 208 I ST 08 53683 ZEITLIN, Benjamin R., M.S. General Foods Corp. Research Center 555 South Broadway Tarry town, NY ZAPP, John A., Ph.D. Director, Haskell Laboratory E.I. du Pont de Nemours &. Co. Newark, DE ZARATZIAN, Virginia, Ph.D. R.A. Taft Sanitary Engineering Center 4676 Columbia Parkway Cincinnati 26, OH ZWICKEY, Robert E., D.V.M. Head, Pathology Unit Merck Inst, for Therapeutic Research West Point, PA ^Indicates Honorary Members 209